Popescu Mihaela, Radivojevic Kristina, Trasca Diana-Maria, Varut Renata Maria, Enache Irina, Osman Andrei
Department of Endocrinology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Research Methodology Department, Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Pharmaceuticals (Basel). 2025 May 4;18(5):682. doi: 10.3390/ph18050682.
Diabetes mellitus (DM) is a chronic disease with a growing prevalence worldwide, leading to severe health complications. Current treatment relies on antidiabetic medications, which may have adverse effects, highlighting the need for alternative approaches. Natural compounds, such as phenolic compounds, have shown promise in glucose modulation. The family includes several plants with potential antidiabetic properties. This review examines the pathophysiology of diabetes, chemical composition, and specific species that have demonstrated antidiabetic effects. Studies indicate that species and other plants can lower blood glucose levels and improve insulin sensitivity through mechanisms such as enzyme inhibition. These findings suggest that plants may serve as complementary strategies for diabetes management.
糖尿病（DM）是一种在全球范围内患病率不断上升的慢性疾病，会导致严重的健康并发症。目前的治疗依赖于抗糖尿病药物，这些药物可能有副作用，这凸显了需要采用替代方法。天然化合物，如酚类化合物，在调节血糖方面已显示出前景。该家族包括几种具有潜在抗糖尿病特性的植物。这篇综述探讨了糖尿病的病理生理学、化学成分以及已证明具有抗糖尿病作用的特定植物种类。研究表明，该植物种类及其他植物可以通过酶抑制等机制降低血糖水平并提高胰岛素敏感性。这些发现表明，该植物可能作为糖尿病管理的补充策略。
