Törős Gréta, Béni Áron, Balláné Andrea Kovács, Semsey Dávid, Ferroudj Aya, Prokisch József
Institute of Animal Science, Biotechnology and Nature Conservation, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, Böszörményi Street 138, 4032 Debrecen, Hungary.
Doctoral School of Animal Husbandry, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, Böszörményi Street 138, 4032 Debrecen, Hungary.
Pharmaceutics. 2025 Apr 30;17(5):591. doi: 10.3390/pharmaceutics17050591.
The study aimed to develop a sustainable method for producing myco-nanomaterials, particularly fluorescent carbon nanodots (CNDs), from freeze-dried (Agaricomycetes) mushroom powder via pyrolysis. The goal was to investigate how pyrolysis conditions affect CND characteristics and their potential antimicrobial properties. Mushroom powder was pyrolyzed at temperatures ranging from 150 to 240 °C. The resulting products were analyzed for yield, molecular weight, fluorescence intensity, and estimated CND concentration in relation to the carbon-to-nitrogen (C/N) ratio. Antibacterial activity was tested against and . Product yield decreased from 13.20% at 150 °C to 0.80% at 240 °C. Molecular weight peaked at 200 °C (623.20 kDa), while maximum fluorescence intensity (739.40 A.U.) was observed at 210 °C. A strong positive correlation (R = 0.72) was found between the C/N ratio and estimated CND concentration. Antimicrobial testing revealed notable inhibition of associated with higher fluorescence intensity and CND content. Pyrolyzed mushroom powder offers a promising, eco-friendly platform for producing luminescent, carbonaceous nanomaterials with antibacterial potential. These non-purified, myco-derived nanomaterials may contribute to green nanotechnology development and antimicrobial strategies.
该研究旨在开发一种可持续的方法，通过热解从冻干的（伞菌纲）蘑菇粉中生产真菌纳米材料，特别是荧光碳纳米点（CND）。目标是研究热解条件如何影响CND的特性及其潜在的抗菌性能。蘑菇粉在150至240°C的温度范围内进行热解。分析所得产物的产率、分子量、荧光强度以及相对于碳氮比（C/N）的估计CND浓度。针对[具体菌种1]和[具体菌种2]测试抗菌活性。产物产率从150°C时的13.20%降至240°C时的0.80%。分子量在200°C时达到峰值（623.20 kDa），而在210°C时观察到最大荧光强度（739.40 A.U.）。发现C/N比与估计的CND浓度之间存在强正相关（R = 0.72）。抗菌测试表明，与较高的荧光强度和CND含量相关，对[具体菌种1]有显著抑制作用。热解的蘑菇粉为生产具有抗菌潜力的发光碳质纳米材料提供了一个有前景的、环保的平台。这些未经纯化的、源自真菌的纳米材料可能有助于绿色纳米技术的发展和抗菌策略。
