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虚拟现实技术结合体育游戏对改善脑损伤患者认知功能的影响研究:一项随机对照试验的荟萃分析

The study of the effect of virtual reality technology combined with sports games on improving cognitive function in patients with brain injury: a meta analysis of randomized controlled trials.

作者信息

Zhang Yuze, Li Haojie, Xiao Hong

机构信息

Department of Martial Arts and Ethnic Traditions, Henan Sport University, Zhengzhou, China.

School of Physical Education, Yunnan Normal University, Yunnan, China.

出版信息

Front Neurol. 2025 May 13;16:1579909. doi: 10.3389/fneur.2025.1579909. eCollection 2025.

Abstract

BACKGROUND

Brain injury is a major public health issue causing cognitive impairment. Key types include traumatic, ischemic, neurological, infectious, metabolic injuries, and stroke. As populations age, brain injury rates rise, making effective cognitive rehabilitation methods increasingly urgent. Virtual reality sports games, blending immersion and training, offer a new rehab solution.

METHODS

Firstly, we registered in the International Prospective Systematic Review Registry (PROSPERO) website. A total of 12 randomized controlled trials were included in this Meta-analysis. Data were analyzed by Meta-analysis using the random effects model in State statistical software. The primary outcome indicator of the study was cognitive function.

RESULTS

This study included 12 RCTs with 540 participants to evaluate the impact of virtual reality exercise on cognitive function in brain-injured patients. The analysis revealed significant cognitive improvement with an SMD of 0.88 (95% CI: 0.59, 1.17),  = 0.019, and I = 51.9% using a random effects model. Sensitivity analysis confirmed robust findings with no significant single study effects. Symmetric funnel plots indicated no publication bias. These results support virtual reality as an effective cognitive intervention for brain-injured patients.

CONCLUSION

Virtual reality (VR) sports games significantly enhanced cognitive function, coordination, and reaction speed in brain-injured patients, thereby boosting their learning motivation and engagement.

SYSTEMATIC REVIEW REGISTRATION

https://www.crd.york.ac.uk/PROSPERO/, identifier CRD42024581533.

摘要

背景

脑损伤是导致认知障碍的一个主要公共卫生问题。主要类型包括创伤性、缺血性、神经性、感染性、代谢性损伤以及中风。随着人口老龄化,脑损伤发生率上升,使得有效的认知康复方法变得日益迫切。融合沉浸感与训练的虚拟现实体育游戏提供了一种新的康复解决方案。

方法

首先,我们在国际前瞻性系统评价注册库(PROSPERO)网站进行了注册。本Meta分析共纳入12项随机对照试验。使用State统计软件中的随机效应模型通过Meta分析对数据进行分析。该研究的主要结局指标为认知功能。

结果

本研究纳入了12项随机对照试验,共540名参与者,以评估虚拟现实运动对脑损伤患者认知功能的影响。分析显示,使用随机效应模型时,标准化均数差为0.88(95%可信区间:0.59,1.17),P = 0.019,I² = 51.9%,认知功能有显著改善。敏感性分析证实了结果的稳健性,无显著的单一研究效应。对称的漏斗图表明无发表偏倚。这些结果支持虚拟现实作为脑损伤患者有效的认知干预手段。

结论

虚拟现实(VR)体育游戏显著增强了脑损伤患者的认知功能、协调性和反应速度,从而提高了他们的学习动机和参与度。

系统评价注册

https://www.crd.york.ac.uk/PROSPERO/,标识符CRD42024581533。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/12108802/09c9be8c4892/fneur-16-1579909-g001.jpg

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