Fordtran J S, Morawski S G, Santa Ana C A
Gastroenterology. 1985 Nov;89(5):1050-3. doi: 10.1016/0016-5085(85)90208-2.
The effect of 12.5 mM magnesium chloride on sodium transport in the human ileum in vivo was investigated using segmental perfusion. Choline chloride was used as a control. During perfusion of a balanced electrolyte solution containing isotopes of sodium and chloride, magnesium reduced unidirectional flux of sodium in both directions across the ileum; magnesium had no statistically significant effect on net sodium absorption, on chloride fluxes, or on potential difference. When sodium-free test solutions were infused, magnesium (and calcium) reduced net sodium secretion compared with choline and potassium. These results suggest that magnesium (and calcium) reduce passive sodium movement across ileal mucosa.
采用节段灌注法研究了12.5 mM氯化镁对人体回肠钠转运的体内效应。以氯化胆碱作为对照。在灌注含有钠和氯同位素的平衡电解质溶液期间，镁降低了钠在回肠两侧的单向通量；镁对钠的净吸收、氯通量或电位差无统计学显著影响。当输注无钠测试溶液时，与胆碱和钾相比，镁（和钙）降低了钠的净分泌。这些结果表明，镁（和钙）减少了钠在回肠黏膜的被动转运。
