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多血症作为一种理解感觉信息编码的概念。

Polysemia as a concept to understand the encoding of sensory information.

作者信息

Ethier Christian, Vaziri Zohreh, Deschênes Martin

机构信息

CERVO Brain Research Center, Université Laval, Quebec, QC, Canada.

出版信息

Front Neurosci. 2025 May 14;19:1588437. doi: 10.3389/fnins.2025.1588437. eCollection 2025.

DOI:10.3389/fnins.2025.1588437
PMID:40438628
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12116520/
Abstract

In this article, we explore the concept of polysemia in sensory information processing within the brain. We suggest that, just as words can have different meanings based on context, sensory inputs are interpreted differently depending on the animal's current state and behavior. Focusing on the trigeminal sensory nuclei in rats, we highlight the role of inhibitory circuits in gating sensory information and propose that sensory signals are polysemic, with their meaning influenced by emotional, hormonal, and motivational factors.

摘要

在本文中,我们探讨了大脑中感觉信息处理过程中的多义性概念。我们认为,正如单词可以根据上下文有不同含义一样,感觉输入会根据动物当前的状态和行为而被不同地解释。以大鼠的三叉神经感觉核为重点,我们强调了抑制性回路在控制感觉信息方面的作用,并提出感觉信号是多义的,其含义受情绪、激素和动机因素的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35d9/12116520/bf62f16ce82d/fnins-19-1588437-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35d9/12116520/bf62f16ce82d/fnins-19-1588437-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35d9/12116520/bf62f16ce82d/fnins-19-1588437-g001.jpg

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本文引用的文献

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Early electrophysiological indicators for predictive processing in audition: a review.早期听觉预测加工的电生理指标:综述
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Ultrastructural basis for craniofacial sensory processing in the brainstem.脑干部位颅面感觉处理的超微结构基础。
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Inhibitory gating of vibrissal inputs in the brainstem.脑干中触须输入的抑制性门控
J Neurosci. 2008 Feb 20;28(8):1789-97. doi: 10.1523/JNEUROSCI.4627-07.2008.
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Neuron numbers in the sensory trigeminal nuclei of the rat: A GABA- and glycine-immunocytochemical and stereological analysis.大鼠感觉三叉神经核中的神经元数量:一项γ-氨基丁酸和甘氨酸免疫细胞化学及体视学分析。
J Comp Neurol. 2005 Dec 26;493(4):538-53. doi: 10.1002/cne.20778.
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P boutons in lamina IX of the rodent spinal cord express high levels of glutamic acid decarboxylase-65 and originate from cells in deep medial dorsal horn.啮齿动物脊髓第IX层中的P型终扣表达高水平的谷氨酸脱羧酶-65,且起源于内侧背角深部的细胞。
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Identification of signal substances in synapses made between primary afferents and their associated axon terminals in the rat trigeminal sensory nuclei.大鼠三叉神经感觉核中初级传入神经与其相关轴突终末之间突触中信号物质的鉴定。
J Comp Neurol. 2000 Mar 13;418(3):299-309.
8
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