Borra Elena, Jones Derek K, Parent Martin, Petit Laurent, Rockland Kathleen S, Rushmore R Jarrett, Szczupak Diego
Neuroscience Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy.
Cardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, UK.
Brain Struct Funct. 2025 May 30;230(5):77. doi: 10.1007/s00429-025-02943-3.
The term "connections" is a commonly used and convenient shorthand for describing the complex organization of the brain, but it can easily lead to an overemphasis on pairwise or point-to-point, source-target network connectivity. Anatomical studies make clear that there are other important features to consider such as divergence and collateralization (axons or bundles branching to multiple targets), convergence (multiple bundles from different sources converging on the same target), and scrambled topography along a trajectory. This short "Did You Know" communication elaborates on several of these features from the anatomical perspective, while inviting continued dialogue with the tractography community in addressing the shared goals of better understanding brain organization.
“连接”一词是描述大脑复杂组织时常用且便捷的简略说法，但它很容易导致过度强调成对或点对点的源 - 目标网络连接。解剖学研究表明，还有其他重要特征需要考虑，例如发散和侧支化（轴突或束分支到多个目标）、汇聚（来自不同源的多个束汇聚到同一目标）以及沿轨迹的拓扑结构混乱。这篇简短的“你知道吗”通讯从解剖学角度阐述了其中的几个特征，同时邀请与纤维束成像领域继续展开对话，以共同致力于更好地理解大脑组织这一目标。
