Kou Ziwei, Wang Yaoyao, Hao Wanming, Li Yanmiao, Yu Xinjuan, Li Yinan, Zhong Yulu, Gong Entong, Wang Tao, Han Wei
Qingdao Medical College, Qingdao University, Qingdao, China.
Department of Respiratory and Critical Medicine, Qingdao Municipal Hospital, University of Health and Rehabilitation Sciences, Qingdao, China.
Front Public Health. 2025 May 16;13:1583265. doi: 10.3389/fpubh.2025.1583265. eCollection 2025.
This study explores the association between physical activity (PA) levels and patterns during adulthood and chronic obstructive pulmonary disease (COPD).
Data from the National Health and Nutrition Examination Survey (NHANES) 2007-2018 was analyzed. A total of 34,392 participants were included. Three physical activity levels groups were categorized: insufficiently active (individuals not meeting the criteria for "Sufficiently active" or "HEPA active"), sufficiently active ((≥3 days of vigorous activities (≥480 MET-min/week), or ≥5 days of moderate activities /walking (≥600 MET-min/week), or ≥5 days of combined activities (≥600 MET-min/week)), HEPA active ((≥3 days of vigorous activities (≥1,500 MET-minutes/week), or ≥7 days of combined activities (≥3,000 MET-min/week)). Five PA patterns groups were categorized: vigorous work activity, moderate work activity, walk/bicycle for transportation, vigorous recreational activity, moderate recreational activity. The relationship between PA and COPD was explored using a multivariable logistic regression model, restricted cubic spline (RCS) analysis, and stratified analysis.
Compared to insufficiently active individuals, being sufficiently active (OR: 0.86, 95% CI = 0.75-0.98, = 0.025) and HEPA active (OR: 0.84, 95% CI = 0.73-0.96, = 0.010) were associated with lower COPD prevalence. Compared to those lacking corresponding PA patterns, low-level (OR: 1.35, 95% CI = 1.12-1.62, = 0.002) and sufficient (OR: 1.19, 95% CI = 1.05-1.35, = 0.006) moderate work activities (OPA) were linked to higher COPD prevalence. Sufficient transportation-related physical activities (TPA) (OR: 0.72, 95% CI = 0.59-0.89, = 0.003), sufficient vigorous recreational activities (RPA) (OR: 0.68, 95% CI = 0.55-0.85, < 0.001), low-level moderate RPA (OR: 0.77, 95% CI = 0.66-0.90, = 0.001), and sufficient moderate RPA (OR: 0.71, 95% CI = 0.61-0.84, < 0.001) were all significantly associated with lower COPD prevalence.
In adulthood, TPA and RPA were associated with a lower COPD prevalence, while OPA were associated with a higher COPD prevalence. However, COPD patients might become less active because of their symptoms, which may influence study results. Increasing TPA/RPA proportion in total PA could be a potential COPD prevention strategy, but causal evidence requires further validation.
本研究探讨成年期身体活动（PA）水平及模式与慢性阻塞性肺疾病（COPD）之间的关联。
分析了2007 - 2018年美国国家健康与营养检查调查（NHANES）的数据。共纳入34392名参与者。将身体活动水平分为三组：活动不足（未达到“充分活动”或“高强度身体活动活跃”标准的个体）、充分活动（每周进行≥3天剧烈活动（≥480代谢当量分钟/周），或≥5天中等强度活动/步行（≥600代谢当量分钟/周），或≥5天组合活动（≥600代谢当量分钟/周））、高强度身体活动活跃（每周进行≥3天剧烈活动（≥1500代谢当量分钟/周），或≥7天组合活动（≥3000代谢当量分钟/周））。将PA模式分为五组：剧烈工作活动、中等强度工作活动、步行/骑自行车出行、剧烈娱乐活动、中等强度娱乐活动。采用多变量逻辑回归模型、受限立方样条（RCS）分析和分层分析探讨PA与COPD之间的关系。
与活动不足的个体相比，充分活动（比值比：0.86，95%置信区间 = 0.75 - 0.98，P = 0.025）和高强度身体活动活跃（比值比：0.84，95%置信区间 = 0.73 - 0.96）与较低的COPD患病率相关。与缺乏相应PA模式的人相比，低水平（比值比：1.35，95%置信区间 =
