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特罗姆瑟心脏研究:冠心病危险因素及其与童年生活条件的关联。

The Tromsø heart study: coronary risk factors and their association with living conditions during childhood.

作者信息

Arnesen E, Forsdahl A

出版信息

J Epidemiol Community Health. 1985 Sep;39(3):210-4. doi: 10.1136/jech.39.3.210.

Abstract

We examined the relation between questionnaire answers concerning living conditions during childhood and coronary risk factors in 7405 men and 7247 women. Poverty during childhood was positively associated with age-adjusted levels (p less than 0.05) of total cholesterol and percentage of current smokers (men only) and negatively associated with body height. When cholesterol was adjusted for age, body mass index, leisure time physical activity, coffee and alcohol consumption, and cigarette smoking there was a significant linear trend in women (p less than or equal to 0.0001) but not in men (p = 0.224). Analysing only subjects born in Troms county, giving a more homogeneous population, the linear trend became significant (p = 0.011) for men also. We conclude that childhood poverty followed by a high standard of living operates, at least partly, as a risk factor for coronary heart disease through conventional risk factors.

摘要

我们调查了7405名男性和7247名女性关于童年生活条件的问卷答案与冠心病风险因素之间的关系。童年时期的贫困与年龄调整后的总胆固醇水平(p<0.05)以及当前吸烟者的百分比(仅男性)呈正相关,与身高呈负相关。当对年龄、体重指数、休闲时间体力活动、咖啡和酒精消费以及吸烟进行调整后,女性中存在显著的线性趋势(p≤0.0001),而男性中则不存在(p = 0.224)。仅分析出生在特罗姆瑟县的受试者(其人群更为同质)时,男性的线性趋势也变得显著(p = 0.011)。我们得出结论,童年贫困后生活水平较高,至少部分地通过传统风险因素,作为冠心病的一个风险因素起作用。

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