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生命历程健康发展:过去、现在与未来。

Lifecourse health development: past, present and future.

机构信息

UCLA Center for Healthier Children, Families, and Communities, 10990 Wilshire Blvd, Suite 900, Los Angeles, CA, 90024, USA,

出版信息

Matern Child Health J. 2014 Feb;18(2):344-65. doi: 10.1007/s10995-013-1346-2.

Abstract

During the latter half of the twentieth century, an explosion of research elucidated a growing number of causes of disease and contributors to health. Biopsychosocial models that accounted for the wide range of factors influencing health began to replace outmoded and overly simplified biomedical models of disease causation. More recently, models of lifecourse health development (LCHD) have synthesized research from biological, behavioral and social science disciplines, defined health development as a dynamic process that begins before conception and continues throughout the lifespan, and paved the way for the creation of novel strategies aimed at optimization of individual and population health trajectories. As rapid advances in epigenetics and biological systems research continue to inform and refine LCHD models, our healthcare delivery system has struggled to keep pace, and the gulf between knowledge and practice has widened. This paper attempts to chart the evolution of the LCHD framework, and illustrate its potential to transform how the MCH system addresses social, psychological, biological, and genetic influences on health, eliminates health disparities, reduces chronic illness, and contains healthcare costs. The LCHD approach can serve to highlight the foundational importance of MCH, moving it from the margins of national debate to the forefront of healthcare reform efforts. The paper concludes with suggestions for innovations that could accelerate the translation of health development principles into MCH practice.

摘要

在二十世纪后半叶,大量的研究揭示了越来越多的疾病原因和健康因素。生物心理社会模型考虑了影响健康的广泛因素,开始取代过时和过于简化的疾病病因的生物医学模型。最近,生命历程健康发展模型(LCHD)综合了来自生物、行为和社会科学领域的研究,将健康发展定义为一个始于受孕前并贯穿整个生命周期的动态过程,为制定旨在优化个体和人口健康轨迹的新策略铺平了道路。随着表观遗传学和生物系统研究的快速进展不断为 LCHD 模型提供信息和完善,我们的医疗保健提供系统努力与之保持同步,知识与实践之间的差距不断扩大。本文试图描绘 LCHD 框架的演变,并说明其改变 MCH 系统应对健康的社会、心理、生物和遗传影响、消除健康差距、减少慢性疾病和控制医疗保健成本的潜力。LCHD 方法可以突出 MCH 的基础重要性,将其从国家辩论的边缘推向医疗改革努力的前沿。本文最后提出了一些创新建议,这些建议可以加速将健康发展原则转化为 MCH 实践。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdb0/3890560/741336d1f596/10995_2013_1346_Fig1_HTML.jpg

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