DNA序列对DNA增强铽（III）荧光的影响。
The influence of DNA sequence on terbium (III) fluorescence enhancement by DNA.
作者信息
Ringer D P, Etheredge J L, Kizer D E
出版信息
J Inorg Biochem. 1985 Jun;24(2):137-45. doi: 10.1016/0162-0134(85)80005-2.
The synthetic DNA duplexes, poly(dA-dC):poly(dG-dT), poly(dG):poly(dC), poly(dG-dC):poly(dG-dC), and poly(dG-m5dC):poly(dG-m5dC), were analyzed as double- and single-strand polymers for the ability to enhance terbium fluorescence. Using conditions which limited the enhancement of Tb3+ fluorescence to that from DNA-guanosines, our results showed that (a) guanosines in single-strand DNA enhanced terbium fluorescence equally well irrespective of the primary sequence surrounding them, and (b) guanosines in either left- (Z-form) or right- (B-form) handed double helixes failed to enhance terbium fluorescence.
对合成的DNA双链体，即聚（dA-dC）：聚（dG-dT）、聚（dG）：聚（dC）、聚（dG-dC）：聚（dG-dC）和聚（dG-m5dC）：聚（dG-m5dC），作为双链和单链聚合物增强铽荧光的能力进行了分析。在将Tb3+荧光增强限制为仅源于DNA鸟苷的条件下，我们的结果表明：（a）单链DNA中的鸟苷，无论其周围的一级序列如何，增强铽荧光的效果同样良好；（b）左手（Z型）或右手（B型）双螺旋中的鸟苷均不能增强铽荧光。
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