Yeli Mahantesh, Naik Balaram, Kulkarni Raghavendra D, Bhat Kishore, Moogi Prashant, Tapashetti Sharmila, Karunakar P
Department of Conservative Dentistry and Endodontics, SDM College of Dental Sciences and Hospital, A Constituent Unit of Sri Dharmasthala Manjunatheshwara University, Dharwad, Telangana, India.
Department of Conservative Dentistry and Endodontics, SDM College of Medical Sciences and Hospital, Dharwad, Telangana, India.
J Conserv Dent Endod. 2025 May;28(5):439-443. doi: 10.4103/JCDE.JCDE_93_25. Epub 2025 May 6.
Persistent endodontic infections often occur due to surviving or reintroduced microorganisms. Thus, effective disinfection is the key point for successful endodontic retreatment. Various advanced techniques have been invented to enhance the effectiveness of NaOCl, the standard irrigant.
The aim of this study was to evaluate the use of photodynamic disinfection with light-emitting diode (LED) and lasers as adjuncts to sodium hypochlorite in endodontic nonsurgical retreatment cases.
Sixty-six symptomatic patients, aged 18-80 years requiring endodontic nonsurgical retreatment, were included. They were divided into three groups: Group ST (sodium hypochlorite), Group SD (LED activation), and Group SL (laser activation). Microbiological samples were collected pre- and postintervention. Microbiological analysis included aerobic/anaerobic cultures and polymerase chain reaction for uncultivable organisms.
Group ST was most effective against and ( = 0.005 and = 0.004, respectively). All groups showed similar effectiveness against unculturable organisms and aerobic microorganisms.
NaOCl is better than both LED and diode laser photoactivated disinfection (PAD) for endodontic retreatment, especially against and . In cases involving , diode laser activation may be a suitable adjunct. While PAD methods contribute to microbial reduction, they do not surpass the efficacy of traditional NaOCl irrigation.
持续性牙髓感染通常是由于存活或再次引入的微生物引起的。因此，有效的消毒是牙髓再治疗成功的关键。人们发明了各种先进技术来提高标准冲洗剂次氯酸钠（NaOCl）的有效性。
本研究的目的是评估在牙髓非手术再治疗病例中，使用发光二极管（LED）和激光进行光动力消毒作为次氯酸钠辅助手段的效果。
纳入66例年龄在18至80岁之间需要进行牙髓非手术再治疗的有症状患者。他们被分为三组：ST组（次氯酸钠）、SD组（LED激活）和SL组（激光激活）。在干预前后收集微生物样本。微生物分析包括需氧/厌氧培养以及针对不可培养微生物的聚合酶链反应。
ST组对[具体微生物1]和[具体微生物2]最有效（分别为P = 0.005和P = 0.004）。所有组对不可培养微生物和好氧微生物显示出相似的有效性。
对于牙髓再治疗，次氯酸钠优于LED和二极管激光光活化消毒（PAD），尤其是对[具体微生物1]和[具体微生物2]。在涉及[具体微生物3]的病例中，二极管激光激活可能是一种合适的辅助手段。虽然PAD方法有助于减少微生物，但它们并未超过传统次氯酸钠冲洗的疗效。
