从宏基因组学解析猪肠道微生物群的组成与功能。

Unraveling the composition and function of pig gut microbiome from metagenomics.

作者信息

Tang Qiwu, Yin Xiaoping, Wen Guihui, Luo Zhang, Zhang Lei, Tan Shengguo

机构信息

Hunan Biological and Electromechanical Polytechnic, Changsha, 410128, China.

Liuyang Agricultural Development Center, Liuyang, 410300, China.

出版信息

Anim Microbiome. 2025 Jun 4;7(1):60. doi: 10.1186/s42523-025-00419-7.

DOI:10.1186/s42523-025-00419-7

PMID:40468444

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12139186/

Abstract

The gut microbiome plays a crucial role in intestinal maturation, metabolism, and immunoregulation, significantly influencing the host's health and growth performance. This review highlights the use of metagenomic techniques to the composition, function, and dynamic changes of the pig gut microbiota. Research has revealed that environmental and host factors, particularly diet, drive significant variations in microbial composition, which in turn shape host epigenetics through microbial components and metabolites. Furthermore, the strong correlation between the gut microbiota and host health presents opportunities for improving growth performance in the livestock industry.

摘要

肠道微生物群在肠道成熟、代谢和免疫调节中起着关键作用，对宿主的健康和生长性能有显著影响。本综述重点介绍了宏基因组技术在猪肠道微生物群的组成、功能和动态变化方面的应用。研究表明，环境和宿主因素，尤其是饮食，会导致微生物组成的显著变化，进而通过微生物成分和代谢产物塑造宿主表观遗传学。此外，肠道微生物群与宿主健康之间的强相关性为提高畜牧业的生长性能提供了机会。