Zhu Ye, Jiang Yong, Lei Lei, Liu Hongchi, Guan Tianmin
School of Mechanical Engineering, Dalian Jiao Tong University, Dalian, China.
Department of Spine Surgery, Dalian Second People's Hospital, Dalian, Liaoning, China.
Front Transplant. 2025 May 22;4:1528548. doi: 10.3389/frtra.2025.1528548. eCollection 2025.
The porous structure can effectively reduce the stress shielding effect in the process of implanting prostheses in the treatment of bone defects, but the performance of different types of porous structures directly affects the treatment effect, so it is necessary to evaluate a variety of different porous structures and select the most suitable structure type for implantation to improve the treatment effect. Based on the three-dimensional model of porous structure, this paper uses numerical analysis to evaluate the mechanical properties of porous structure and completes the primary selection of porous structure; secondly, the indexes and weights affecting the performance of porous structure are clarified, the calculation method of evaluation value is determined, and the evaluation system of implanted prosthesis with porous structure is constructed; then, through mechanical experiments and animal experiments, the machinability index and bone ingrowth index of the primary structure and commonly used clinical structure are studied; finally, according to the evaluation system, the most suitable type of porous structure for implantation is selected. The results of this study found that the tetrahedral body-centered structure [diamond structure] is the optimal structure type for the preparation of implanted prostheses with porous structures. The implantation of tetrahedral body-heart structure is of great significance for the treatment of segmental bone defects and can improve the quality of life of patients.
多孔结构在骨缺损治疗中植入假体的过程中可有效降低应力遮挡效应，但不同类型多孔结构的性能直接影响治疗效果，因此有必要评估多种不同的多孔结构并选择最合适的结构类型进行植入以提高治疗效果。基于多孔结构的三维模型，本文采用数值分析方法评估多孔结构的力学性能并完成多孔结构的初选；其次，明确影响多孔结构性能的指标及权重，确定评价值的计算方法，构建多孔结构植入假体的评价体系；然后，通过力学实验和动物实验，研究初选结构和临床常用结构的加工性能指标和骨长入指标；最后，根据评价体系选择最适合植入的多孔结构类型。本研究结果发现，四面体体心结构[菱形结构]是制备多孔结构植入假体的最佳结构类型。四面体心结构的植入对节段性骨缺损的治疗具有重要意义，可提高患者的生活质量。
