Wali Luqman, Rowbotham Emma
Radiology Department, Royal National Orthopaedic Hospital NHS Trust, London, UK.
Radiology Department, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Rheumatol Adv Pract. 2025 Jun 4;9(2):rkaf051. doi: 10.1093/rap/rkaf051. eCollection 2025.
Gout is a common systemic disease defined by deposition of monosodium urate (MSU) crystals in articular and peri-articular structures, leading to recurrent bouts of inflammation. Imaging plays an important role in establishing the diagnosis when crystal aspiration is not feasible and the clinical diagnosis is uncertain. Each imaging modality has a unique role. Radiographs can demonstrate characteristic erosions and tophi in later stages of gout. Ultrasound has a major role in the diagnosis and assessment of gout. Dual-energy computed tomography (DECT) enables precise visualization of MSU deposits and can determine disease burden. MRI can assess for non-specific inflammatory and structural changes. Both ultrasound and DECT are emphasized as part of diagnostic algorithms and the role of imaging is expanding with more recent advancements and evidence. This review provides an imaging-centric overview of each modality and its evolving significance in gout.
痛风是一种常见的全身性疾病,其定义为单钠尿酸盐(MSU)晶体在关节及关节周围结构中沉积,导致反复发作的炎症。当无法进行晶体抽吸且临床诊断不确定时,影像学检查在确立诊断方面发挥着重要作用。每种影像学检查方法都有其独特的作用。X线平片在痛风后期可显示特征性的骨质侵蚀和痛风石。超声在痛风的诊断和评估中起主要作用。双能计算机断层扫描(DECT)能够精确显示MSU沉积物,并可确定疾病负担。MRI可评估非特异性炎症和结构改变。超声和DECT均被强调为诊断流程的一部分,且随着最新进展和证据的出现,影像学检查的作用正在不断扩展。本综述以影像学为中心,概述了每种检查方法及其在痛风中不断演变的意义。