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Gouty Arthropathy: Review of Clinical Manifestations and Treatment, with Emphasis on Imaging.

作者信息

Weaver Jennifer S, Vina Ernest R, Munk Peter L, Klauser Andrea S, Elifritz Jamie M, Taljanovic Mihra S

机构信息

Department of Radiology, University of New Mexico, Albuquerque, NM 87131, USA.

Department of Medicine, University of Arizona Arthritis Center, Tucson, AZ 85724, USA.

出版信息

J Clin Med. 2021 Dec 29;11(1):166. doi: 10.3390/jcm11010166.


DOI:10.3390/jcm11010166
PMID:35011907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8745871/
Abstract

Gout, a crystalline arthropathy caused by the deposition of monosodium urate crystals in the articular and periarticular soft tissues, is a frequent cause of painful arthropathy. Imaging has an important role in the initial evaluation as well as the treatment and follow up of gouty arthropathy. The imaging findings of gouty arthropathy on radiography, ultrasonography, computed tomography, dual energy computed tomography, and magnetic resonance imaging are described to include findings of the early, acute and chronic phases of gout. These findings include early monosodium urate deposits, osseous erosions, and tophi, which may involve periarticular tissues, tendons, and bursae. Treatment of gout includes non-steroidal anti-inflammatories, colchicine, glucocorticoids, interleukin-1 inhibitors, xanthine oxidase inhibitors, uricosuric drugs, and recombinant uricase. Imaging is critical in monitoring response to therapy; clinical management can be modulated based on imaging findings. This review article describes the current standard of care in imaging and treatment of gouty arthropathy.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/7210da2fcbc6/jcm-11-00166-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/3e6ca1225130/jcm-11-00166-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/a56fcacaa4da/jcm-11-00166-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/f202345cc2ad/jcm-11-00166-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/3b0f271eee4d/jcm-11-00166-g004a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/f25757b5bfb9/jcm-11-00166-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/ad72a1134186/jcm-11-00166-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/664241b38ce8/jcm-11-00166-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/f1a7dfd641d5/jcm-11-00166-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/d53643a9fcaf/jcm-11-00166-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/83afb2d16f86/jcm-11-00166-g010a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/a11a41f2641d/jcm-11-00166-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/e455da8d7484/jcm-11-00166-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/715d85fd4883/jcm-11-00166-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/7210da2fcbc6/jcm-11-00166-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/3e6ca1225130/jcm-11-00166-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/a56fcacaa4da/jcm-11-00166-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/f202345cc2ad/jcm-11-00166-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/3b0f271eee4d/jcm-11-00166-g004a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/f25757b5bfb9/jcm-11-00166-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/ad72a1134186/jcm-11-00166-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/664241b38ce8/jcm-11-00166-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/f1a7dfd641d5/jcm-11-00166-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/d53643a9fcaf/jcm-11-00166-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/83afb2d16f86/jcm-11-00166-g010a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/a11a41f2641d/jcm-11-00166-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/e455da8d7484/jcm-11-00166-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/715d85fd4883/jcm-11-00166-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009b/8745871/7210da2fcbc6/jcm-11-00166-g014.jpg

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引用本文的文献

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Eur J Orthop Surg Traumatol. 2025-6-23

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[3]
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Front Surg. 2025-5-13

[4]
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[5]
Auricular Gouty Tophi: A Rare Presentation in an Uncommon Site.

Cureus. 2025-3-23

[6]
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[7]
Pictorial Review of Soft Tissue Lesions with Calcification.

Diagnostics (Basel). 2025-3-22

[8]
Risk of Gout Among Patients With Tuberculosis: A Nationwide Cohort Study in South Korea.

Int J Rheum Dis. 2025-3

[9]
Tophaceous Gout in the Axial Skeleton: An Unusual Case with Key Imaging Characteristics.

Kans J Med. 2025-2-17

[10]
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本文引用的文献

[1]
The role of dual energy computed tomography in the differentiation of acute gout flares and acute calcium pyrophosphate crystal arthritis.

Clin Rheumatol. 2022-1

[2]
Pulsed Electromagnetic Fields in Bone Healing: Molecular Pathways and Clinical Applications.

Int J Mol Sci. 2021-7-9

[3]
Two-year reduction of dual-energy CT urate depositions during a treat-to-target strategy in gout in the NOR-Gout longitudinal study.

Rheumatology (Oxford). 2022-4-18

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Sonographic estimation of monosodium urate burden predicts the fulfillment of the 2016 remission criteria for gout: a 12-month study.

Arthritis Res Ther. 2021-7-9

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A Randomized, Phase II Study Evaluating the Efficacy and Safety of Anakinra in the Treatment of Gout Flares.

Arthritis Rheumatol. 2021-8

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Semin Arthritis Rheum. 2021-6

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Rheumatology (Oxford). 2021-10-2

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Ann Acad Med Singap. 2020-11

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Ultrasonography and dual-energy computed tomography: impact for the detection of gouty deposits.

Ultrasonography. 2021-4

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UltraSound evaluation in follow-up of urate-lowering therapy in gout phase 2 (USEFUL-2): Duration of flare prophylaxis.

Joint Bone Spine. 2020-12

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