Goswami Mridula, Johnson Riya Marie, Jangra Babita
Pediatric and Preventive Dentistry, Maulana Azad Institute of Dental Sciences, New Delhi, IND.
Cureus. 2025 May 6;17(5):e83554. doi: 10.7759/cureus.83554. eCollection 2025 May.
Silver diamine fluoride (SDF) is a minimally invasive treatment modality that has gained attention in recent years owing to its remineralizing capability. However, there is limited research on its effect at a microscopic level. This case series presents three cases of exfoliated primary teeth where histologic and morphological analysis was performed after a single application of SDF on carious dentin. This paper provides valuable insights into the long-term and sustained effectiveness of SDF, making it a cost-effective treatment for young, uncooperative children including those with special health care needs. In addition, it also highlights that periodic re-application of SDF can enhance the overall caries-arresting potential. However, despite the clinical success, the inclusion of silver particles deep within the dentinal tubules results in pronounced discoloration, which is a significant drawback of SDF. Future research has to be directed toward innovative techniques to overcome discoloration while maintaining its efficacy.
氟化亚银（SDF）是一种微创治疗方式，近年来因其再矿化能力而受到关注。然而，关于其在微观层面的作用的研究有限。本病例系列展示了三例乳牙脱落病例，在对龋坏牙本质单次应用SDF后进行了组织学和形态学分析。本文提供了关于SDF长期持续有效性的宝贵见解，使其成为治疗年幼、不合作儿童（包括有特殊医疗需求的儿童）的一种经济有效的治疗方法。此外，它还强调定期重新应用SDF可以增强整体防龋潜力。然而，尽管临床取得了成功，但牙本质小管深处包含银颗粒会导致明显变色，这是SDF的一个重大缺点。未来的研究必须致力于创新技术，以在保持其疗效的同时克服变色问题。
