Lee D, Flowerday M H, Tomlinson J
Vox Sang. 1977;32(4):189-94. doi: 10.1111/j.1423-0410.1977.tb00628.x.
Attempts to produce anti-D in rhesus-negative men using reconstituted frozen rhesus-positive cells were unsuccessful. The use of cells coated with IgM anti-D for immunisation stimulates anti-D production, and a comparison between two groups, one having cells coated with IgM anti-D, and the other having identical cells without coating suggests that there is an enhancement of the immune response when IgM-coated cells are used.
尝试使用重构的冷冻恒河猴阳性细胞在恒河猴阴性男性体内产生抗-D未获成功。使用包被有IgM抗-D的细胞进行免疫可刺激抗-D产生,对两组进行比较,一组使用包被有IgM抗-D的细胞,另一组使用相同但未包被的细胞,结果表明使用包被有IgM的细胞时免疫反应增强。