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全身型幼年类风湿关节炎中的短暂性血小板减少症。

Transient thrombocytopenia in systemic onset juvenile rheumatoid arthritis.

作者信息

Sherry D D, Kredich D W

出版信息

Pediatrics. 1985 Oct;76(4):600-3.

PMID:4047803
Abstract

Three children have been presented who have had long-standing, typical systemic juvenile rheumatoid arthritis. They also had a transient illness with thrombocytopenia, antiplatelet antibodies, and the simultaneous appearance of anti-DNA antibodies and hypocomplementemia. Other single abnormalities included the development of a positive ANA, Coombs, and lupus bands test. All responded to high-dose steroid therapy. Their similar clinical and serologic findings are noteworthy and represent one of the numerous complications seen in patients with systemic juvenile rheumatoid arthritis.

摘要

本文报告了3例患有长期典型全身型幼年类风湿关节炎的儿童。他们还曾患过一种短暂性疾病,伴有血小板减少、抗血小板抗体,同时出现抗DNA抗体和补体降低。其他单一异常包括抗核抗体、库姆斯试验和狼疮带试验呈阳性。所有患儿对大剂量类固醇治疗均有反应。他们相似的临床和血清学表现值得关注,代表了全身型幼年类风湿关节炎患者中众多并发症之一。

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