Hartmeyer Steffen L, Phillips Nicholas E, Jassil Friedrich C, Joris Céline, Dibner Charna, Collet Tinh-Hai, Andersen Marilyne
Laboratory of Integrated Performance in Design (LIPID), School of Architecture, Civil and Environmental Engineering (ENAC), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Service of Endocrinology and Diabetology, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland.
Acta Physiol (Oxf). 2025 Jul;241(7):e70069. doi: 10.1111/apha.70069.
As our understanding of light's impact on human health grows, studies examining light exposure and related health outcomes in everyday settings are increasingly important, particularly in high-risk groups like nightshift workers.
In this observational study, we monitored personal light exposure and physiological functions in a large cohort of healthcare nightshift workers using a spectrally resolved light dosimeter and wearable body temperature, actigraphy, and electrocardiography sensors.
Our findings revealed a common occurrence of unfavorable light conditions during both shift types. During nightshift work, participants frequently experienced exposure to biologically potent cool-white LED lighting. On dayshifts, melanopic light levels often failed to meet recommended guidelines, with daylight as the primary source of bright light levels. Sleep duration, but not quality, significantly varied between shifts, with longer sleep before the first nightshift but shorter sleep on subsequent nights. Daytime and nighttime napping helped compensate for reduced sleep on nightshifts. Limited associations between light exposure and sleep were found, partially contradicting existing knowledge. Diurnal physiological and activity rhythms followed the change from day-active to night-active schedules; however, the change in physiological rhythms appeared partly dissociated from that of activity, suggesting a circadian modulation. Moreover, physiological functions exhibited bi-directional phase-shifts across consecutive nightshifts, which may have been mediated by differences in daytime light exposure before the first nightshift.
By employing a multi-wearable approach including recent sensors, we provide new insights into the lighting environments experienced by nightshift workers and the potential impact of nightshift work and light exposure on endogenous circadian rhythms.
随着我们对光对人类健康影响的认识不断加深，研究日常环境中的光照暴露及相关健康结果变得越发重要，尤其是在夜班工作者等高风险人群中。
在这项观察性研究中，我们使用光谱分辨光剂量计以及可穿戴式体温、活动记录仪和心电图传感器，对一大群医疗保健夜班工作者的个人光照暴露和生理功能进行了监测。
我们的研究结果显示，两种轮班类型期间均普遍存在不利的光照条件。在夜班工作期间，参与者经常暴露于具有生物活性的冷白色LED照明下。在白班期间，黑素视蛋白光照水平常常未能达到推荐标准，主要明亮光照水平的来源是日光。轮班之间的睡眠时间有显著差异，但睡眠质量无显著差异，在第一个夜班前睡眠时间较长，但在随后的夜晚睡眠时间较短。白天和夜间小睡有助于弥补夜班时减少的睡眠。发现光照暴露与睡眠之间的关联有限，部分与现有知识相矛盾。昼夜生理和活动节律随着从白天活跃到夜间活跃的时间表变化而变化；然而，生理节律的变化似乎部分与活动变化脱节，表明存在昼夜调节。此外，生理功能在连续夜班期间呈现双向相移，这可能是由第一个夜班前白天光照暴露的差异介导的。
通过采用包括最新传感器在内的多可穿戴设备方法，我们对夜班工作者所经历的照明环境以及夜班工作和光照暴露对内源性昼夜节律的潜在影响提供了新的见解。
