Lyu Jingran, Song Dongyu, Pan Yaoyi, Lin Weiyi, Li Yuli, Dai Yunpeng, Ho Ka Yan, Han Yuanyuan
School of Nursing and Rehabilitation, Shandong University, Jinan, China.
Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Asia Pac J Oncol Nurs. 2025 Apr 26;12:100709. doi: 10.1016/j.apjon.2025.100709. eCollection 2025 Dec.
A child's cancer diagnosis is a significant family event, and there is a need to explore factors that influence the quality of life of children with cancer from family-based perspectives. This study aimed to explore the interrelationships between parental burnout, sibling relationship quality, and quality of life in children with cancer.
This cross-sectional study enrolled 218 children with cancer and their parents in three tertiary hospitals in Shandong Province using convenience sampling. Children completed the Chinese version of the Pediatric Quality of Life Inventory 4.0, while their parents completed the Parental Perceptions of Children's Sibling Relationship Quality Questionnaire and Maslach Burnout Inventory, and provided their own sociodemographic information, as well as their children's sociodemographic and clinical characteristics. Network analysis was employed to examine the relationships between variables.
In the overall network, social functioning in children with cancer exhibited the highest strength ( = 1.03), while warmth in sibling relationship quality showed the highest bridge strength ( = 0.42). Social functioning was positively associated with warmth in sibling relationship quality ( = 0.15), and negatively associated with personal achievement ( = -0.13) and depersonalization ( = -0.09) in parental burnout. Emotional functioning was negatively associated with emotional exhaustion in parental burnout ( = -0.10) and jealousy in sibling relationship quality ( = -0.10).
There are significant interrelationships between the network structure of family related variables and quality of life in children with cancer. These findings offer guidance for healthcare professionals focusing on family-based interventions to improve the quality of life of children with cancer.
儿童癌症诊断是一件重大的家庭事件，有必要从家庭角度探索影响癌症儿童生活质量的因素。本研究旨在探讨父母倦怠、同胞关系质量与癌症儿童生活质量之间的相互关系。
本横断面研究采用便利抽样法，纳入了山东省三家三级医院的218名癌症儿童及其父母。儿童完成中文版儿童生活质量量表4.0，而他们的父母完成儿童同胞关系质量的父母认知问卷和马氏倦怠量表，并提供自己的社会人口学信息以及孩子的社会人口学和临床特征。采用网络分析来检验变量之间的关系。
在整体网络中，癌症儿童的社会功能表现出最高强度（β = 1.03），而同胞关系质量中的温暖度表现出最高的桥接强度（β = 0.42）。社会功能与同胞关系质量中的温暖度呈正相关（β = 0.15），与父母倦怠中的个人成就感（β = -0.13）和去个性化（β = -0.09）呈负相关。情绪功能与父母倦怠中的情感耗竭（β = -0.10）和同胞关系质量中的嫉妒感（β = -0.10）呈负相关。
家庭相关变量的网络结构与癌症儿童的生活质量之间存在显著的相互关系。这些发现为专注于家庭干预以提高癌症儿童生活质量的医护人员提供了指导。
