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一名患有特发性性早熟的青春期前女孩的青少年纤维腺瘤:一例挑战激素范式的病例报告

Juvenile Fibroadenoma in a Prepubertal Girl With Idiopathic Precocious Puberty: A Case Report Challenging Hormonal Paradigms.

作者信息

Bensaghir Hamza, Abbassi Asma, Ben Driss Chaimae, Rami Mohamed, Bouhafs Mohamed El Amine

机构信息

Department of Pediatric Surgery, Children's Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.

出版信息

Cureus. 2025 May 9;17(5):e83779. doi: 10.7759/cureus.83779. eCollection 2025 May.

Abstract

Juvenile fibroadenoma (JF) is a rare benign breast tumor that predominantly occurs in adolescent and young adult females. However, its occurrence in prepubertal girls is exceedingly rare and poses diagnostic and therapeutic challenges. We present a case of a six-year-old girl with a rapidly growing breast mass, ultimately diagnosed as juvenile fibroadenoma. This case highlights the importance of considering JF in the differential diagnosis of breast masses in pediatric patients, even in very young children. The clinical presentation, diagnostic workup, and management of JF are discussed, along with a review of the literature to provide insights into this rare condition.

摘要

青少年纤维腺瘤(JF)是一种罕见的乳腺良性肿瘤,主要发生于青春期及年轻成年女性。然而,其在青春期前女孩中的发生极为罕见,并且带来了诊断和治疗方面的挑战。我们报告一例6岁女孩,其乳腺肿块迅速增大,最终被诊断为青少年纤维腺瘤。该病例强调了在儿科患者乳腺肿块的鉴别诊断中考虑JF的重要性,即使是在非常年幼的儿童中。本文讨论了青少年纤维腺瘤的临床表现、诊断检查及治疗,并对相关文献进行综述,以深入了解这一罕见病症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/12145663/2a369d1258fe/cureus-0017-00000083779-i01.jpg

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