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一名患有特发性性早熟的青春期前女孩的青少年纤维腺瘤:一例挑战激素范式的病例报告

Juvenile Fibroadenoma in a Prepubertal Girl With Idiopathic Precocious Puberty: A Case Report Challenging Hormonal Paradigms.

作者信息

Bensaghir Hamza, Abbassi Asma, Ben Driss Chaimae, Rami Mohamed, Bouhafs Mohamed El Amine

机构信息

Department of Pediatric Surgery, Children's Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.

出版信息

Cureus. 2025 May 9;17(5):e83779. doi: 10.7759/cureus.83779. eCollection 2025 May.

DOI:10.7759/cureus.83779
PMID:40486348
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12145663/
Abstract

Juvenile fibroadenoma (JF) is a rare benign breast tumor that predominantly occurs in adolescent and young adult females. However, its occurrence in prepubertal girls is exceedingly rare and poses diagnostic and therapeutic challenges. We present a case of a six-year-old girl with a rapidly growing breast mass, ultimately diagnosed as juvenile fibroadenoma. This case highlights the importance of considering JF in the differential diagnosis of breast masses in pediatric patients, even in very young children. The clinical presentation, diagnostic workup, and management of JF are discussed, along with a review of the literature to provide insights into this rare condition.

摘要

青少年纤维腺瘤(JF)是一种罕见的乳腺良性肿瘤,主要发生于青春期及年轻成年女性。然而,其在青春期前女孩中的发生极为罕见,并且带来了诊断和治疗方面的挑战。我们报告一例6岁女孩,其乳腺肿块迅速增大,最终被诊断为青少年纤维腺瘤。该病例强调了在儿科患者乳腺肿块的鉴别诊断中考虑JF的重要性,即使是在非常年幼的儿童中。本文讨论了青少年纤维腺瘤的临床表现、诊断检查及治疗,并对相关文献进行综述,以深入了解这一罕见病症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/12145663/1dd796a49e79/cureus-0017-00000083779-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/12145663/2a369d1258fe/cureus-0017-00000083779-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/12145663/e2f72f597d4f/cureus-0017-00000083779-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/12145663/89ed20bc7a58/cureus-0017-00000083779-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/12145663/1dd796a49e79/cureus-0017-00000083779-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/12145663/2a369d1258fe/cureus-0017-00000083779-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/12145663/e2f72f597d4f/cureus-0017-00000083779-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/12145663/89ed20bc7a58/cureus-0017-00000083779-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/12145663/1dd796a49e79/cureus-0017-00000083779-i05.jpg

相似文献

1
Juvenile Fibroadenoma in a Prepubertal Girl With Idiopathic Precocious Puberty: A Case Report Challenging Hormonal Paradigms.一名患有特发性性早熟的青春期前女孩的青少年纤维腺瘤:一例挑战激素范式的病例报告
Cureus. 2025 May 9;17(5):e83779. doi: 10.7759/cureus.83779. eCollection 2025 May.
2
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[Giant juvenile fibroadenoma - a benign and rare tumour of the breast in adolescent girls].[巨大青少年纤维腺瘤——青春期女孩乳房的一种良性罕见肿瘤]
Ugeskr Laeger. 2014 Mar 3;176(10A).
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本文引用的文献

1
Literature Review of Periclitoral Cysts in the Prepubertal Population.青春期前人群阴蒂周围囊肿的文献综述
J Pediatr Adolesc Gynecol. 2016 Dec;29(6):558-561. doi: 10.1016/j.jpag.2016.05.005. Epub 2016 May 27.
2
A family systems approach to primary ovarian insufficiency.一种针对原发性卵巢功能不全的家庭系统方法。
J Pediatr Adolesc Gynecol. 2011 Jun;24(3):137-41. doi: 10.1016/j.jpag.2010.12.004. Epub 2011 Jan 26.
3
Breast core needle biopsy: issues and controversies.乳腺芯针活检:问题与争议。
Mod Pathol. 2010 May;23 Suppl 2:S36-45. doi: 10.1038/modpathol.2010.34.
4
Fibroadenomas in adolescence.青少年纤维腺瘤
Curr Opin Obstet Gynecol. 2009 Oct;21(5):402-6. doi: 10.1097/GCO.0b013e32832fa06b.
5
Incidence and management of complex fibroadenomas.复杂型纤维腺瘤的发病率及管理
AJR Am J Roentgenol. 2008 Jan;190(1):214-8. doi: 10.2214/AJR.07.2330.
6
Phyllodes tumours.叶状肿瘤
Postgrad Med J. 2001 Jul;77(909):428-35. doi: 10.1136/pmj.77.909.428.
7
Breast US in children and adolescents.儿童和青少年的乳腺超声检查
Radiographics. 2000 Nov-Dec;20(6):1605-12. doi: 10.1148/radiographics.20.6.g00nv171605.
8
Management of breast fibroadenomas.乳腺纤维腺瘤的管理
J Gen Intern Med. 1998 Sep;13(9):640-5. doi: 10.1046/j.1525-1497.1998.cr188.x.
9
Prevalence and longitudinal study of breast masses in adolescents.青少年乳腺肿块的患病率及纵向研究
J Adolesc Health. 1993 Jun;14(4):277-81. doi: 10.1016/1054-139x(93)90174-n.
10
Adenomas of the breast and ectopic breast under lactational influences.哺乳期影响下的乳腺腺瘤及异位乳腺
Hum Pathol. 1985 Jul;16(7):707-12. doi: 10.1016/s0046-8177(85)80156-8.