Greenberg R, Skornick Y, Kaplan O
Department of Surgery A, Tel-Aviv Medical Center, and the Sackler Faculty of Medicine, Tel-Aviv University, Israel.
J Gen Intern Med. 1998 Sep;13(9):640-5. doi: 10.1046/j.1525-1497.1998.cr188.x.
To identify from the literature and clinical experience a rational approach to management of fibroadenomas of the breast.
Recent literature on detection, diagnosis, and natural history of fibroadenomas was reviewed. Experience with over 4,000 women evaluated in the breast clinic at the Tel-Aviv Medical Center contributed to the management strategies suggested by review of the literature.
Fibroadenomas of the breast are common, accounting for 50% of all breast biopsies performed. Physical examination, sonography, and fine needle aspiration are effective in distinguishing fibroadenomas from breast cancer. Transformation from fibroadenoma to cancer is rare; regression or resolution is frequent, supporting conservative approaches to follow-up and management.
Age-based algorithms that allow for conservative management and that limit excision to patients whose fibroadenomas fail to regress are presented.
从文献和临床经验中确定一种合理的乳腺纤维瘤管理方法。
回顾了关于乳腺纤维瘤的检测、诊断及自然史的近期文献。在特拉维夫医疗中心乳腺诊所对4000多名女性的评估经验为文献综述所提出的管理策略提供了依据。
乳腺纤维瘤很常见，占所有乳腺活检的50%。体格检查、超声检查和细针穿刺在区分乳腺纤维瘤和乳腺癌方面很有效。乳腺纤维瘤转变为癌症的情况很少见；消退或消失很常见，这支持了随访和管理的保守方法。
提出了基于年龄的算法，该算法允许保守管理，并将切除限制于纤维瘤未消退的患者。
