Gaertner David, Stölzel Katharina, Wright Felicia, von Bargen Clara Marie, Böttcher Arne
Department of Otorhinolaryngology, University Medical Center Hamburg-Eppendorf, Hamburg, DEU.
Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, DEU.
Cureus. 2025 May 8;17(5):e83739. doi: 10.7759/cureus.83739. eCollection 2025 May.
We present the case of a 38-year-old female patient diagnosed with a solitary fibrous tumor (SFT) of the right hypopharynx, a rare and atypical localization of this mesenchymal neoplasm. SFT is a rare entity. Most SFTs are benign tumors commonly arising in the pleura, while extrapleural occurrence in locations such as the head and neck region is also well recognized. The aim of this report is to describe this rare clinical presentation, discuss the diagnostic complexities it entails, and emphasize the critical role of complete surgical excision as the mainstay of treatment, as radiation or chemotherapy protocols are not well established or have been proven to be ineffective. Recurrence is mostly associated with incomplete resection, and malignant transformations have been described. Given the challenging anatomic location of the tumor in our patient, a total laryngectomy was required to achieve complete tumor removal.
我们报告一例38岁女性患者,诊断为右下咽孤立性纤维瘤(SFT),这是这种间叶性肿瘤罕见且不典型的定位。SFT是一种罕见的实体瘤。大多数SFT是常见于胸膜的良性肿瘤,而在头颈部等部位的胸膜外发生也已得到充分认识。本报告的目的是描述这种罕见的临床表现,讨论其所带来的诊断复杂性,并强调完整手术切除作为主要治疗手段的关键作用,因为放疗或化疗方案尚未确立或已被证明无效。复发大多与切除不完全有关,并且已有恶性转化的描述。鉴于我们患者肿瘤具有挑战性的解剖位置,需要进行全喉切除术以实现肿瘤的完全切除。