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十二指肠溃疡穿孔性腹膜炎作为小儿急腹症的病因:1例罕见病例报告及文献复习

Duodenal ulcer perforation peritonitis as a cause of acute abdomen in pediatric population: a rare case report and review of literature.

作者信息

Suraj K C, Yogi Tek Nath, Rauniyar Krish, Sah Rajesh Prasad, Bhusal Amrit, Kafle Rijan, Malla Nakendra, Gahatraj Manish

机构信息

Department of Surgery, BP Koirala Institute of Health Sciences (BPKIHS), Dharan, Nepal.

出版信息

Ann Med Surg (Lond). 2025 Apr 29;87(6):3915-3919. doi: 10.1097/MS9.0000000000003315. eCollection 2025 Jun.

Abstract

INTRODUCTION

Acute abdomen in pediatric patients presents diagnostic challenges due to the wide range of potential causes and overlapping clinical features. Duodenal ulcer perforation, though rare, can mimic more common conditions like appendicitis, complicating diagnosis and management. Perforated peptic ulcer disease (PUD) in children, especially without chronic nonsteroidal anti-inflammatory drug (NSAID) use or infection, is uncommon but requires prompt recognition.

CASE PRESENTATION

A 9-year-old male presented with severe diffuse abdominal pain, fever, and a history of chills. Physical examination revealed tenderness, board-like rigidity, and sluggish bowel sounds. Laboratory tests showed leukocytosis, but radiological findings, including abdominal X-ray, were normal. Ultrasound indicated gaseous abdomen and fluid collection. An exploratory laparotomy revealed a perforation in the first part of the duodenum, which was repaired using a Graham omental patch. Postoperatively, the patient recovered well with intravenous antibiotics and was discharged on the sixth postoperative day.

CLINICAL DISCUSSION

Duodenal ulcer perforation, though rare, should be considered in pediatric cases of acute abdomen. Common causes of PUD include infection, NSAIDs, and stress-related ulcers. Diagnosis is often delayed, particularly when typical radiological signs like pneumoperitoneum are absent, as in this case. Timely surgical intervention is critical to prevent morbidity and mortality.

CONCLUSION

Duodenal ulcer perforation should be considered as a potential cause of peritonitis in children with acute abdomen, even in the absence of typical radiographic signs. Early recognition and surgical intervention are essential for favorable outcomes.

摘要

引言

小儿急腹症因潜在病因广泛且临床特征重叠而带来诊断挑战。十二指肠溃疡穿孔虽罕见,但可酷似阑尾炎等更常见病症,使诊断和治疗复杂化。儿童消化性溃疡穿孔疾病(PUD),尤其是无慢性非甾体抗炎药(NSAID)使用史或感染情况的,并不常见,但需要及时识别。

病例介绍

一名9岁男性因严重弥漫性腹痛、发热及寒战病史就诊。体格检查发现压痛、板状腹及肠鸣音减弱。实验室检查显示白细胞增多,但包括腹部X线在内的影像学检查结果正常。超声显示气腹和液体积聚。剖腹探查发现十二指肠第一部穿孔,采用格雷厄姆网膜补片进行修复。术后,患者通过静脉使用抗生素恢复良好,并于术后第六天出院。

临床讨论

十二指肠溃疡穿孔虽罕见,但在小儿急腹症病例中应予以考虑。PUD的常见病因包括感染、NSAIDs及应激相关溃疡。诊断常被延迟,特别是在像本例这样缺乏气腹等典型影像学征象时。及时的手术干预对于预防发病和死亡至关重要。

结论

即使没有典型的影像学征象,十二指肠溃疡穿孔也应被视为小儿急腹症并发腹膜炎的潜在病因。早期识别和手术干预对于取得良好预后至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39ba/12140785/c0798466b3d9/ms9-87-3915-g001.jpg

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