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基于术前动态对比增强磁共振成像(DCE-MRI)和人工智能(AI),采用直接前路入路取出钽棒的全髋关节置换术:一例报告

Total hip arthroplasty with tantalum rod extraction via direct anterior approach based on preoperative DCE-MRI and AI: a case report.

作者信息

Zhiyuan Chen, Jiahao Sun, Bowen Ma, Tianwei Xia, Jirong Shen

机构信息

Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.

出版信息

Ann Med Surg (Lond). 2025 May 21;87(6):3894-3901. doi: 10.1097/MS9.0000000000003286. eCollection 2025 Jun.

Abstract

INTRODUCTION AND IMPORTANCE

Osteonecrosis of the femoral head (ONFH) is a debilitating condition characterized by compromised blood supply to the femoral head, leading to bone marrow or osteocyte death, and ultimately resulting in ischemia, necrosis, and potential collapse of the femoral head. Dynamic contrast-enhanced MRI (DCE-MRI) is a minimally invasive test that has the advantage of providing a microenvironmental picture of the femoral head that cannot be detected by conventional imaging (e.g., X-rays, CT, MR), and accurately assessing the viability and function of the local tissues, thus helping to select the appropriate surgical intervention. In this context, tantalum rod implantation has been employed as a treatment option for ONFH, aiming to provide structural support and potentially improve blood supply to the necrotic area. However, there are few reports in the literature on the evaluation of the efficacy of tantalum rod implantation in combination with DCE-MRI.

CASE PRESENTATION

A patient with bilateral SONFH, diagnosed according to the ARCO classification, presented with significant pain and limited mobility. Despite undergoing tantalum rod implantation in both hips, the patient reported minimal improvement in symptoms and continued to experience discomfort. Preoperative DCE-MRI was conducted to assess blood supply in the femoral heads, revealing inadequate perfusion in the necrotic areas. Given the poor response to tantalum rod implantation, a decision was made to proceed with DAA-THA to remove the tantalum rods and femoral heads. Intraoperative findings confirmed the presence of necrotic bone and lack of significant revascularization in the affected areas. The retrieved femoral head specimens were subjected to pathological and micro-CT analysis, which further confirmed the extent of necrosis and the inadequacy of blood supply.

CLINICAL DISCUSSION

The use of tantalum rods in the treatment of ONFH is based on their osteoconductive properties and potential to promote revascularization. However, the success of this treatment is highly dependent on the preoperative blood supply status of the femoral head. DCE-MRI played a crucial role in this case by providing a clear picture of blood perfusion in the necrotic areas, which helped in identifying patients who may not benefit from tantalum rod implantation. The pathological and micro-CT analysis of the retrieved femoral head specimens provided additional insights into the reasons behind the inefficacy of tantalum rod implantation. Specifically, the lack of significant revascularization and the extent of necrosis highlighted the limitations of this treatment option in certain patient populations. The decision to proceed with DAA-THA was based on the patient's poor response to tantalum rod implantation and the need for a definitive surgical intervention. The use of the AIHIP system for preoperative planning facilitated a precise and efficient surgical approach, minimizing trauma and optimizing postoperative recovery.

CONCLUSION

This case study highlights the importance of comprehensive preoperative assessment using DCE-MRI in guiding the selection of surgical interventions for ONFH. Specifically, DCE-MRI can identify patients who may not respond favorably to tantalum rod implantation due to inadequate blood supply in the necrotic areas. In such cases, alternative treatment options such as DAA-THA should be considered.

摘要

引言与重要性

股骨头坏死(ONFH)是一种使人衰弱的病症,其特征是股骨头血液供应受损,导致骨髓或骨细胞死亡,最终导致股骨头缺血、坏死并可能塌陷。动态对比增强磁共振成像(DCE-MRI)是一种微创检查,具有能够提供股骨头微观环境图像的优势,而这是传统成像(如X射线、CT、MR)无法检测到的,并且能准确评估局部组织的活力和功能,从而有助于选择合适的手术干预措施。在此背景下,钽棒植入已被用作ONFH的一种治疗选择,旨在提供结构支撑并有可能改善坏死区域的血液供应。然而,关于钽棒植入联合DCE-MRI疗效评估的文献报道较少。

病例介绍

一名根据ARCO分类诊断为双侧股骨头坏死的患者,出现严重疼痛和活动受限。尽管双侧髋关节均接受了钽棒植入,但患者报告症状改善甚微,仍持续感到不适。术前进行了DCE-MRI以评估股骨头的血液供应,结果显示坏死区域灌注不足。鉴于对钽棒植入反应不佳,决定进行双动全髋关节置换术(DAA-THA)以取出钽棒和股骨头。术中发现证实了坏死骨的存在以及受影响区域缺乏明显的血管再生。取出的股骨头标本进行了病理和显微CT分析,进一步证实了坏死程度和血液供应不足。

临床讨论

在ONFH治疗中使用钽棒是基于其骨传导特性和促进血管再生的潜力。然而,这种治疗的成功高度依赖于股骨头术前的血液供应状况。在本病例中,DCE-MRI通过清晰显示坏死区域的血液灌注情况发挥了关键作用,这有助于识别可能无法从钽棒植入中获益的患者。对取出的股骨头标本进行的病理和显微CT分析为钽棒植入无效的原因提供了更多见解。具体而言,缺乏明显的血管再生和坏死程度凸显了该治疗方案在某些患者群体中的局限性。决定进行DAA-THA是基于患者对钽棒植入反应不佳以及需要确定性手术干预。使用AIHIP系统进行术前规划有助于实现精确、高效的手术方法,最大限度地减少创伤并优化术后恢复。

结论

本病例研究强调了在指导ONFH手术干预选择时使用DCE-MRI进行全面术前评估的重要性。具体而言,DCE-MRI可以识别由于坏死区域血液供应不足而可能对钽棒植入反应不佳的患者。在这种情况下,应考虑如DAA-THA等替代治疗方案。

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