Zhang Hui, Wen Yupeng, Lai Ngit Shin
Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, George Town, Pulau Pinang, Malaysia.
College of Medicine, Huanghuai University, Zhumadian, Henan, China.
Medicine (Baltimore). 2025 Jun 6;104(23):e42695. doi: 10.1097/MD.0000000000042695.
FcγR (Fc gamma receptor) is a glycoprotein involved in various biological activities, such as inflammation and tumor immunity, and new ideas about the role of FcγR have also been published recently. Our study utilized journals derived from those published from 2004 to 2024 to analyze the research hotspots and cutting-edge ideas in this field.
All publications were searched using the web of science core collection database. VOSviewer, the R package Biblioshiny in R-studio and CiteSpace (version 6.1.R6) were utilized to perform bibliometric analysis which focused on authors, countries, organizations, keywords, etc.
The analysis of this article is based on 6849 articles related to FcγR from 107 countries and 37,487. The most cited reference in FcγR field is the article "Fcgamma Receptors as Regulators of Immune Responses," authored by Nimmerjahn. Country/region analysis shows that the United States of America (USA) has far more citation frequency and publications than other countries. The most recent hotspots and keywords are "COVID-19" and "SARS-CoV-2."
Through bibliometric analysis, we can clearly recognize the evolution of the field of FcγR research, from the original cellular immunity to tumor immunity to the occurrence of the latest viral immunity, which may guide the direction of research in the field and allow researchers to be more aware of the current status and frontiers of the field.
FcγR(Fcγ受体)是一种参与多种生物活性的糖蛋白,如炎症和肿瘤免疫,并且最近也发表了关于FcγR作用的新观点。我们的研究利用了2004年至2024年发表的期刊来分析该领域的研究热点和前沿观点。
使用科学网核心合集数据库搜索所有出版物。利用VOSviewer、R-studio中的R包Biblioshiny和CiteSpace(版本6.1.R6)进行文献计量分析,重点关注作者、国家、组织、关键词等。
本文的分析基于来自107个国家的6849篇与FcγR相关的文章以及37487篇文献。FcγR领域被引用次数最多的参考文献是Nimmerjahn撰写的文章“Fcγ受体作为免疫反应的调节因子”。国家/地区分析表明,美国的被引用频率和出版物数量远远超过其他国家。最新的热点和关键词是“COVID-19”和“SARS-CoV-2”。
通过文献计量分析,我们可以清楚地认识到FcγR研究领域的演变,从最初的细胞免疫到肿瘤免疫再到最新的病毒免疫的出现,这可能会指导该领域的研究方向,并让研究人员更了解该领域的现状和前沿。