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Fcγ受体的研究热点与趋势：2004年至2024年的文献计量分析

The hot spots and trends of Fc gamma receptor: A bibliometric analysis from 2004 to 2024.

作者信息

Zhang Hui, Wen Yupeng, Lai Ngit Shin

机构信息

Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, George Town, Pulau Pinang, Malaysia.

College of Medicine, Huanghuai University, Zhumadian, Henan, China.

出版信息

Medicine (Baltimore). 2025 Jun 6;104(23):e42695. doi: 10.1097/MD.0000000000042695.

DOI:10.1097/MD.0000000000042695
PMID:40489867
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12150913/
Abstract

INTRODUCTION

FcγR (Fc gamma receptor) is a glycoprotein involved in various biological activities, such as inflammation and tumor immunity, and new ideas about the role of FcγR have also been published recently. Our study utilized journals derived from those published from 2004 to 2024 to analyze the research hotspots and cutting-edge ideas in this field.

METHOD

All publications were searched using the web of science core collection database. VOSviewer, the R package Biblioshiny in R-studio and CiteSpace (version 6.1.R6) were utilized to perform bibliometric analysis which focused on authors, countries, organizations, keywords, etc.

RESULT

The analysis of this article is based on 6849 articles related to FcγR from 107 countries and 37,487. The most cited reference in FcγR field is the article "Fcgamma Receptors as Regulators of Immune Responses," authored by Nimmerjahn. Country/region analysis shows that the United States of America (USA) has far more citation frequency and publications than other countries. The most recent hotspots and keywords are "COVID-19" and "SARS-CoV-2."

DISCUSSION

Through bibliometric analysis, we can clearly recognize the evolution of the field of FcγR research, from the original cellular immunity to tumor immunity to the occurrence of the latest viral immunity, which may guide the direction of research in the field and allow researchers to be more aware of the current status and frontiers of the field.

摘要

引言

FcγR（Fcγ受体）是一种参与多种生物活性的糖蛋白，如炎症和肿瘤免疫，并且最近也发表了关于FcγR作用的新观点。我们的研究利用了2004年至2024年发表的期刊来分析该领域的研究热点和前沿观点。

方法

使用科学网核心合集数据库搜索所有出版物。利用VOSviewer、R-studio中的R包Biblioshiny和CiteSpace（版本6.1.R6）进行文献计量分析，重点关注作者、国家、组织、关键词等。

结果

本文的分析基于来自107个国家的6849篇与FcγR相关的文章以及37487篇文献。FcγR领域被引用次数最多的参考文献是Nimmerjahn撰写的文章“Fcγ受体作为免疫反应的调节因子”。国家/地区分析表明，美国的被引用频率和出版物数量远远超过其他国家。最新的热点和关键词是“COVID-19”和“SARS-CoV-2”。

讨论

通过文献计量分析，我们可以清楚地认识到FcγR研究领域的演变，从最初的细胞免疫到肿瘤免疫再到最新的病毒免疫的出现，这可能会指导该领域的研究方向，并让研究人员更了解该领域的现状和前沿。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8679/12150913/4e7b06031e87/medi-104-e42695-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8679/12150913/2f20d15f4536/medi-104-e42695-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8679/12150913/ac8150896e4a/medi-104-e42695-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8679/12150913/e66c21160b1a/medi-104-e42695-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8679/12150913/7d42304bbfb4/medi-104-e42695-g008.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8679/12150913/4e7b06031e87/medi-104-e42695-g010.jpg

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本文引用的文献

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Sci Transl Med. 2024 Sep 25;16(766):eadj1277. doi: 10.1126/scitranslmed.adj1277.
2
Fc-FcγR interactions during infections: From neutralizing antibodies to antibody-dependent enhancement.感染过程中的Fc-FcγR相互作用：从中和抗体到抗体依赖增强作用
Immunol Rev. 2024 Nov;328(1):221-242. doi: 10.1111/imr.13393. Epub 2024 Sep 13.
3
Neuronal C-Reactive Protein/FcγRI Positive Feedback Proinflammatory Signaling Contributes to Nerve Injury Induced Neuropathic Pain.
神经元 C 反应蛋白/FcγRI 正反馈炎症信号促进神经损伤诱导的神经性疼痛。
Adv Sci (Weinh). 2023 Apr;10(10):e2205397. doi: 10.1002/advs.202205397. Epub 2023 Feb 2.
4
Worldwide Research Trends on Diabetic Foot Ulcers (2004-2020): Suggestions for Researchers.全球糖尿病足溃疡研究趋势（2004-2020）：对研究人员的建议。
J Diabetes Res. 2022 Jan 27;2022:7991031. doi: 10.1155/2022/7991031. eCollection 2022.
5
Role of Fcγ receptors in HER2-targeted breast cancer therapy.Fcγ 受体在曲妥珠单抗治疗 HER2 阳性乳腺癌中的作用
J Immunother Cancer. 2022 Jan;10(1). doi: 10.1136/jitc-2021-003171.
6
Bibliometrics: Methods for studying academic publishing.文献计量学：学术出版研究方法。
Perspect Med Educ. 2022 Jun;11(3):173-176. doi: 10.1007/s40037-021-00695-4. Epub 2021 Dec 16.
7
Are Fc Gamma Receptor Polymorphisms Important in HIV-1 Infection Outcomes and Latent Reservoir Size?Fc 伽马受体多态性在 HIV-1 感染结局和潜伏 reservoir 大小中重要吗？
Front Immunol. 2021 May 4;12:656894. doi: 10.3389/fimmu.2021.656894. eCollection 2021.
8
Visualizing a field of research: A methodology of systematic scientometric reviews.可视化研究领域：系统文献计量学综述方法。
PLoS One. 2019 Oct 31;14(10):e0223994. doi: 10.1371/journal.pone.0223994. eCollection 2019.
9
Cartilage-binding antibodies induce pain through immune complex-mediated activation of neurons.软骨结合抗体通过免疫复合物介导的神经元激活引起疼痛。
J Exp Med. 2019 Aug 5;216(8):1904-1924. doi: 10.1084/jem.20181657. Epub 2019 Jun 13.
10
Targeting the Antibody Checkpoints to Enhance Cancer Immunotherapy-Focus on FcγRIIB.靶向抗体检查点以增强癌症免疫治疗 - 聚焦于 FcγRIIB。
Front Immunol. 2019 Mar 12;10:481. doi: 10.3389/fimmu.2019.00481. eCollection 2019.