Fengxia Chen, Jin Dexiang, Lian Ailing
Nursing School, North Henan Medical University, China.
Operating Room, The First Affiliated Hospital of Harbin Medical University, China.
J Int Med Res. 2025 Jun;53(6):3000605251347553. doi: 10.1177/03000605251347553. Epub 2025 Jun 10.
ObjectiveThe use of energy devices during surgery can cause the spread of surgical smoke into the operating room. The concentration of smoke particles during laparoscopic surgery is higher than that during open surgery. This study aimed to quantify polycyclic aromatic hydrocarbons during laparoscopic surgery and evaluate the carcinogenic risks to healthcare workers, as the current relevant data are insufficient.MethodsThis prospective observational study collected and classified surgical smoke generated during laparoscopic surgery. Quantitative and qualitative analyses of polycyclic aromatic hydrocarbons were performed using gas chromatography-mass spectrometry.ResultsMultiple types of polycyclic aromatic hydrocarbons were generated during laparoscopic surgery. The polycyclic aromatic hydrocarbon concentrations remained below the carcinogenic risk levels in both laparoscopic liver cancer surgery and rectal cancer resection procedures.ConclusionThe deposition pattern and concentration of polycyclic aromatic hydrocarbons generated during laparoscopic liver and rectal cancer resection surgeries in the human respiratory tract are different. The potential toxicity of polycyclic aromatic hydrocarbons in the smoke to the health of healthcare workers should not be ignored.
目的
手术过程中使用能量设备会导致手术烟雾扩散到手术室。腹腔镜手术期间烟雾颗粒的浓度高于开放手术期间。由于目前相关数据不足，本研究旨在对腹腔镜手术期间的多环芳烃进行定量，并评估对医护人员的致癌风险。
方法
这项前瞻性观察性研究收集并分类了腹腔镜手术期间产生的手术烟雾。使用气相色谱 - 质谱法对多环芳烃进行定量和定性分析。
结果
腹腔镜手术期间产生了多种类型的多环芳烃。在腹腔镜肝癌手术和直肠癌切除手术中，多环芳烃浓度均保持在致癌风险水平以下。
结论
腹腔镜肝癌和直肠癌切除手术中产生的多环芳烃在人体呼吸道中的沉积模式和浓度不同。烟雾中多环芳烃对医护人员健康的潜在毒性不容忽视。
