Diop Solene, Lyon Elsa, Van Caenegem Nicolas, Escriou Catherine, Freiche Valérie, Blot Stéphane
Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort, France.
Univ Paris Est Créteil, INSERM, U955 IMRB "Biology of the Neuromuscular System" Team, Maisons-Alfort, France.
J Vet Intern Med. 2025 Jul-Aug;39(4):e70158. doi: 10.1111/jvim.70158.
In human medicine, focal seizures can clinically express as autonomic signs, such as gastrointestinal dysfunction, cardiovascular changes, and variation of pupillary size; but little is known about possible presentations of autonomic seizures in veterinary medicine. Three dogs were presented for recurrent episodes characterized by hypersalivation, vomiting, retching, and signs of abdominal discomfort. Neurological examinations were normal between episodes. Electroencephalographic (EEG) recordings identified ictal or interictal epileptiform discharges in all dogs. Based on clinical signs and EEG findings, a diagnosis of focal autonomic seizures was made. There was a notable positive response of clinical signs to antiepileptic treatment. These cases highlight the diverse clinical presentations of focal autonomic seizures in dogs and emphasize the diagnostic value of EEG in these cases.
在人类医学中,局灶性癫痫发作在临床上可表现为自主神经症状,如胃肠功能紊乱、心血管变化和瞳孔大小改变;但在兽医学中,关于自主神经癫痫发作的可能表现知之甚少。三只犬只因反复出现以流涎过多、呕吐、干呕和腹部不适迹象为特征的发作而就诊。发作间期的神经学检查均正常。脑电图(EEG)记录在所有犬只中均发现发作期或发作间期癫痫样放电。根据临床症状和脑电图检查结果,诊断为局灶性自主神经癫痫发作。临床症状对抗癫痫治疗有显著的阳性反应。这些病例突出了犬局灶性自主神经癫痫发作的多样临床表现,并强调了脑电图在这些病例中的诊断价值。