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禽致病性菌株VTB96933v的完整序列,该菌株含有一种新型的具有接合抗菌抗性和毒力的IncI1-ST114-ColBM质粒。

Complete sequence of the avian pathogenic strain VTB96933v containing a novel conjugative antimicrobial resistance and virulence IncI1-ST114-ColBM plasmid.

作者信息

Wang Zhuohao, Gerber David, Perreten Vincent

机构信息

Division of Molecular Bacterial Epidemiology & Infectious Diseases, Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.

出版信息

Microbiol Resour Announc. 2025 Jul 10;14(7):e0028425. doi: 10.1128/mra.00284-25. Epub 2025 Jun 12.

Abstract

The complete sequence of a South African avian pathogenic was obtained through short and long read consensus-based assembly. It consists of a 5,120,371 bp chromosome and two plasmids, one of 86,932 and the other of 161,786 bp. The latter is a novel conjugative ColBM plasmid type IncI1-ST114, containing antimicrobial resistance and APEC-associated virulence genes.

摘要

通过基于短读长和长读长的一致性组装获得了一株南非禽致病性菌株的完整序列。它由一条5,120,371 bp的染色体和两个质粒组成,一个质粒大小为86,932 bp,另一个为161,786 bp。后者是一种新型的接合型ColBM质粒,属于IncI1-ST114型,含有抗微生物耐药性基因和与禽致病性大肠杆菌(APEC)相关的毒力基因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ccb/12243562/ceb437efb8b1/mra.00284-25.f001.jpg

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