Ahmadi Hekmatikar Amirhossein
Department of Physical Education and Sport Sciences, Faculty of Humanities, Tarbiat Modares University, Tehran, 10600, Iran.
Cancer Cell Int. 2025 Jun 12;25(1):210. doi: 10.1186/s12935-025-03842-7.
In recent years, researchers have increasingly emphasized the significance of exercise in cancer treatment from the perspective of exercise oncology. Additionally, there has been growing interest in the potential role of medicinal plants in cancer therapy. However, the term "cancer treatment" encompasses numerous critical considerations, among which immunological factors are particularly significant. A recent and noteworthy review by Liu et al. (2025) [1], titled The Interplay of Exercise and Green Tea: A New Road in Cancer Therapy, explored novel perspectives on the roles of exercise and green tea in cancer treatment. While their analysis provides valuable insights, it unfortunately overlooks the crucial aspect of immunological changes, instead focusing primarily on the mechanisms through which physical activity and green tea contribute to cancer therapy. Given the centrality of immunological responses in cancer treatment, it is essential to examine the immunological changes induced by exercise and green tea, as well as their potential interactions. The failure to address these immunological aspects represents a significant research gap. In this article, we aim to bridge this gap by highlighting the immunological changes associated with exercise and green tea, thereby contributing new perspectives to future studies in the field.
近年来，从运动肿瘤学的角度来看，研究人员越来越强调运动在癌症治疗中的重要性。此外，药用植物在癌症治疗中的潜在作用也越来越受到关注。然而，“癌症治疗”这一术语包含众多关键因素，其中免疫因素尤为重要。刘等人（2025年）[1]最近发表的一篇值得注意的综述《运动与绿茶的相互作用：癌症治疗的新途径》探讨了运动和绿茶在癌症治疗中作用的新观点。虽然他们的分析提供了有价值的见解，但遗憾的是，它忽略了免疫变化这一关键方面，而是主要关注身体活动和绿茶促进癌症治疗的机制。鉴于免疫反应在癌症治疗中的核心地位，研究运动和绿茶引起的免疫变化及其潜在相互作用至关重要。未能解决这些免疫方面的问题代表了一个重大的研究空白。在本文中，我们旨在通过强调与运动和绿茶相关的免疫变化来填补这一空白，从而为该领域未来的研究贡献新的观点。
