Gupta Shalini, Junaniya Ashi, Ahuja Avani, Anjana Radha
Department of Obstetrics and Gynecology, Dr. Laxmi Narayan Pandey Government Medical College, Ratlam Madhya Pradesh, India.
J Pharm Bioallied Sci. 2025 May;17(Suppl 1):S733-S735. doi: 10.4103/jpbs.jpbs_1597_24. Epub 2025 Apr 25.
Researching how women's emotional, cognitive, and cardiovascular changes relate to cyclic changes and its correlation with various stages of the menstrual cycle is crucial.
To assess the effect of various phases of the menstrual cycle on autonomic reactivity to emotional and cognitive stressors.
The present study assessed 124 eumenorrheic females in the age range of 18-20 years, where emotional and cognitive stressors were assessed as emotional Stroop test and PASAT that was conducted on the 10 day and 20 day of the menstrual cycle depicting the follicular and luteal day after determining phases with prism calendar and basal body temperature. DBP, SBP, and HR were assessed at baseline and following stressors. The results were compared in two phases.
At baseline, DBP, SBP, and HR were higher in the luteal phase compared to the follicular phase. PASAT showed that HR recovery was 3.30 min and 4.10 min in the follicular and luteal phases, respectively. SBP recovery was 2.20 min and 2.50 min in the follicular and luteal phases, respectively. DBP recovery was 1.40 min and 2.10 min in the follicular and luteal phases, respectively. In the emotional Stroop test positive, word latency was 1256.435 and 1034.52 ms in the follicular and luteal phases, respectively. Negative word latency was 1145.784 and 1335.302 ms in the follicular and luteal phases, respectively.
The luteal phase presents higher SNS reactivity and thus, emotional and cognitive stressors gather more sympathetic activity; finally, a definitive interaction is seen in the gonadal hormones and higher cognitive centers of female subjects.
研究女性的情绪、认知和心血管变化如何与周期性变化相关，以及其与月经周期各阶段的相关性至关重要。
评估月经周期各阶段对情绪和认知应激源自主反应性的影响。
本研究评估了124名年龄在18 - 20岁的月经周期正常的女性，通过情绪Stroop测试和PASAT评估情绪和认知应激源，测试在月经周期的第10天和第20天进行，使用棱镜日历和基础体温确定阶段后，分别代表卵泡期和黄体期。在基线和应激源刺激后评估舒张压（DBP）、收缩压（SBP）和心率（HR）。结果在两个阶段进行比较。
在基线时，黄体期的DBP、SBP和HR高于卵泡期。PASAT显示，卵泡期和黄体期的心率恢复分别为3.30分钟和4.10分钟。卵泡期和黄体期的SBP恢复分别为2.20分钟和2.50分钟。卵泡期和黄体期的DBP恢复分别为1.40分钟和2.10分钟。在情绪Stroop测试阳性中，卵泡期和黄体期的阳性词潜伏期分别为1256.435毫秒和1034.52毫秒。阴性词潜伏期在卵泡期和黄体期分别为1145.784毫秒和1335.302毫秒。
黄体期呈现出更高的交感神经系统反应性，因此，情绪和认知应激源会引发更多的交感神经活动；最终，在女性受试者的性腺激素和高级认知中枢之间观察到明确的相互作用。
