McCabe D P, Farrar W B, Petkov T M, Finkelmeier W, O'Dwyer P, James A
Am J Surg. 1985 Oct;150(4):519-23. doi: 10.1016/0002-9610(85)90167-9.
Findings in our series of patients and a review of the literature seem to suggest that metastatic cancer to the thyroid is much more common that is clinically evident. The clinical presentation of an asymptomatic mass, normal thyroid functions, and a cold nodule on thyroid scan can occur months to years after treatment of a primary cancer and thus often produces a clinical dilemma. Workup should include ruling out other metastatic cancer and fine-needle aspiration of the thyroid mass. If isolated metastatic cancer to the thyroid is found, surgical resection should be performed, usually by lobectomy and isthmusectomy. Unfortunately, the prognosis is poor, but surgery often prolongs the disease-free interval and occasionally will be curative.
我们一系列患者的研究结果以及文献回顾似乎表明，甲状腺转移性癌比临床所见更为常见。无症状肿块、甲状腺功能正常以及甲状腺扫描显示冷结节的临床表现，可能在原发性癌症治疗数月至数年之后出现，因此常常造成临床困境。检查应包括排除其他转移性癌以及对甲状腺肿块进行细针穿刺抽吸。如果发现孤立性甲状腺转移性癌，通常应行叶切除术和峡部切除术进行手术切除。不幸的是，预后较差，但手术常常会延长无病间期，偶尔还能治愈。
