Low P A, Fealey R D, Sheps S G, Su W P, Trautmann J C, Kuntz N L
Ann Neurol. 1985 Sep;18(3):344-8. doi: 10.1002/ana.410180312.
We describe the cases of eight patients with chronic idiopathic anhidrosis. These patients were heat intolerant and became hot, flushed, dizzy, dyspneic, and weak but did not sweat when the ambient temperature was high or when they exercised. Four patients had preganglionic sudomotor lesions and in the remaining 4 the lesion appeared to be postganglionic. The patients did not have orthostatic hypotension, other evidence of generalized autonomic failure, or symptomatic somatic neuropathy. One patient regained thermoregulatory sweat function and no patient's condition progressed to generalized autonomic failure. Chronic idiopathic anhidrosis appears to be distinctly different from other autonomic neuropathies that tend to carry much poorer prognoses.
我们描述了8例慢性特发性无汗症患者的病例。这些患者不耐热，在环境温度高或运动时会出现发热、脸红、头晕、呼吸困难和虚弱，但不出汗。4例患者有节前汗腺运动神经病变，其余4例病变似乎位于节后。患者没有直立性低血压、其他全身性自主神经功能衰竭的证据或有症状的躯体神经病变。1例患者恢复了体温调节性出汗功能，没有患者的病情进展为全身性自主神经功能衰竭。慢性特发性无汗症似乎与其他往往预后较差的自主神经病变明显不同。
