Scher R K, Tom D W, Lally E V, Bogaars H A
Arch Dermatol. 1985 Nov;121(11):1406-9.
In vivo capillary microscopic findings and proximal nail fold biopsy specimens from 19 patients with various connective tissue diseases, idiopathic Raynaud's phenomenon, and non-connective tissue diseases were studied. Periodic acid-Schiff-positive serous cuticular deposits were not specific to the group of patients with connective tissue disease. Generally, the severity of deposits correlated with the severity of the in vivo capillary microscopic pattern but not with disease severity or duration. The finding of these cuticular deposits may help to identify those patients with idiopathic Raynaud's phenomenon who are at risk to develop a connective tissue disease.
对19例患有各种结缔组织疾病、特发性雷诺现象和非结缔组织疾病的患者进行了体内毛细血管显微镜检查和近端甲襞活检标本研究。高碘酸-希夫染色阳性的浆液性表皮沉积物并非结缔组织疾病患者组所特有。一般来说，沉积物的严重程度与体内毛细血管显微镜检查模式的严重程度相关，但与疾病严重程度或病程无关。这些表皮沉积物的发现可能有助于识别那些有发展为结缔组织疾病风险的特发性雷诺现象患者。
