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[雷诺现象中甲床毛细血管镜检查的适应证]

[Indications for nailbed capillaroscopy in Raynaud's phenomenon].

作者信息

Chamot A M, Monti M

出版信息

Schweiz Med Wochenschr. 1985 Dec 21;115(51):1852-7.

PMID:4089584
Abstract

175 patients with Raynaud's phenomenon underwent nailfold capillaroscopy. 22 had suspected connective tissue diseases, 48 idiopathic Raynaud's disease and 105 a variety of other diagnoses. A normal capillaroscopy is fully consistent with Raynaud's disease. A pathological capillaroscopy with megacapillaries prompts suspicion of underlying connective tissue disease. The other abnormal capillaroscopies are suggestive of Raynaud's phenomenon secondary to one of the numerous associated diseases, and do not rule out evolution to connective disease ("waiting group"). The proposed simplified classification seems to offer reasonably good discrimination. The probability of an abnormal capillaroscopy increases with the age of onset of Raynaud's phenomenon but is not insignificant in younger patients. The (53-year-old) Allen's criterion (3 years follow-up without signs of underlying diseases such as scleroderma, etc.) is disappointing and should be discarded. Nailfold capillaroscopy is a non-invasive procedure which is useful at any age.

摘要

175例雷诺现象患者接受了甲襞毛细血管镜检查。其中22例怀疑患有结缔组织病,48例为特发性雷诺病,105例有各种其他诊断。正常的毛细血管镜检查结果与雷诺病完全相符。出现巨型毛细血管的病理性毛细血管镜检查结果提示可能存在潜在的结缔组织病。其他异常的毛细血管镜检查结果提示雷诺现象继发于众多相关疾病之一,且不能排除发展为结缔组织病的可能性(“观察组”)。所提出的简化分类似乎具有较好的鉴别能力。毛细血管镜检查异常的概率随雷诺现象发病年龄的增加而升高,但在年轻患者中也并非微不足道。(53岁的)艾伦标准(随访3年无硬皮病等潜在疾病迹象)令人失望,应予以摒弃。甲襞毛细血管镜检查是一种无创检查方法,在任何年龄都很有用。

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