Yao Dongmei, Yang Shenbi, Wen Zhifei, He Jing, Ji Shuyang, Xia Minhang, Wang Hongyan, Zhang Xiangeng
Department of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, PR China.
West China Second University Hospital, Sichuan University, Chengdu 610044, PR China.
Arch Gerontol Geriatr. 2025 Oct;137:105935. doi: 10.1016/j.archger.2025.105935. Epub 2025 Jun 7.
To systematically evaluate the factors associated with multidimensional frailty assessed by the Tilburg Frailty Indicator among community-dwelling older adults.
A computerized search was conducted on ten databases, including CNKI, WanFang, VIP, CBM, PubMed, Web of Science, Embase, Scopus, Cochrane Library, and CINAHL, covering studies from inception to December 3, 2024. Literature screening, quality assessment, and data extraction were performed independently by two investigators, and meta-analysis was performed using STATA 18 software. The quality of the evidence was evaluated using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach.
A total of 28 articles with 138,924 participants were included, and 18 influencing factors were extracted. Meta-analysis results showed that: aged(OR=1.19), female(OR=1.53), marital status(no spouse) (OR=2.02), rural residence (OR=1.32), low education level(OR=2.53), fear of falling (OR=5.38), drinking (OR=1.20), smoking(OR=1.12), unhealthy lifestyle (OR=2.52), sleep disorders (OR=2.40), depression(OR=1.52), chronic diseases (OR=2.06), comorbidity (OR=2.08), self-rated poor health(OR=1.89), and hospitalization (OR=1.34) were risk factors for multidimensional frailty in community-dwelling older adults. Satisfaction with living conditions(OR=0.22), physical activity (OR=0.74), and consumption of tea (OR=0.53)were protective factors.
There are many factors involved in the incidence of multidimensional frailty in community-dwelling older adults by a meta-analysis. Screening for multidimensional frailty in community-dwelling older adults can be carried out early based on their risk factors, and corresponding measures can be taken according to the factors that can be intervened in order to delay or reduce the multidimensional frailty in community-dwelling older adults.
系统评价社区居住老年人中与蒂尔堡衰弱指标评估的多维衰弱相关的因素。
对十个数据库进行计算机检索，包括中国知网、万方、维普、中国生物医学文献数据库、PubMed、科学引文索引、Embase、Scopus、考克兰图书馆和护理学与健康领域数据库，涵盖从创刊到2024年12月3日的研究。由两名研究人员独立进行文献筛选、质量评估和数据提取，并使用STATA 18软件进行荟萃分析。采用推荐分级、评估、制定与评价（GRADE）方法评估证据质量。
共纳入28篇文章，138924名参与者，提取出18个影响因素。荟萃分析结果显示：年龄（比值比[OR]=1.19）、女性（OR=1.53）、婚姻状况（无配偶）（OR=2.02）、农村居住（OR=1.32）、低教育水平（OR=2.53）、害怕跌倒（OR=5.38）、饮酒（OR=1.20）、吸烟（OR=1.12）、不健康生活方式（OR=2.52）、睡眠障碍（OR=2.40）、抑郁（OR=1.52）、慢性病（OR=2.06）并发疾病（OR=2.08）、自评健康状况差（OR=1.89）和住院（OR=1.34）是社区居住老年人多维衰弱的危险因素。对生活条件的满意度（OR=0.22）、身体活动（OR=0.74）和饮茶（OR=0.53）是保护因素。
通过荟萃分析可知，社区居住老年人多维衰弱的发生涉及多种因素。可根据社区居住老年人的危险因素早期筛查多维衰弱，并根据可干预因素采取相应措施，以延缓或减少社区居住老年人的多维衰弱。
