Winokur G
Arch Gen Psychiatry. 1985 Nov;42(11):1116-22. doi: 10.1001/archpsyc.1985.01790340100014.
A family history of alcoholism can be used as a validating factor in the diagnosis of reactive-neurotic depression. Not only is this true but there are clear data that indicate the presence of positive symptoms that can be used to make the diagnosis. A set of criteria based on previous research is presented for the diagnosis of neurotic-reactive depression. These criteria are based on a clustering of certain symptoms, events, and traits in patients with neurotic-reactive depression. The patients showed stormy life-styles, some specific symptoms, personality abnormalities, presence of life events before the onset of depression, and a family history of alcoholism. They had relatively few hospitalizations for depression and responded poorly to specific antidepressant treatment.
酗酒家族史可作为反应性神经症性抑郁症诊断的一个验证因素。不仅如此，还有明确数据表明存在可用于诊断的阳性症状。本文提出了一套基于先前研究的诊断神经症性反应性抑郁症的标准。这些标准基于神经症性反应性抑郁症患者的某些症状、事件和特征的聚类。患者表现出动荡的生活方式、一些特定症状、人格异常、抑郁发作前存在生活事件以及酗酒家族史。他们因抑郁症住院的次数相对较少，对特定的抗抑郁治疗反应不佳。
