Rymaszewski Z, Sprinkle D J, Yunker R L, Subbiah M T
Biochem Biophys Res Commun. 1985 Sep 16;131(2):707-11. doi: 10.1016/0006-291x(85)91295-1.
The activity of Acyl CoA-cholesterol acyl transferase was markedly high in fetal aortas when compared to maternal and adult male rabbits. This activity dropped by 50% at 1 week of age. This high activity in fetal aorta a) did not appear to be due to changes in plasma cholesterol levels or to the later development of endogenous inhibitor in the aorta, but rather b) due to stimulatory factor(s) present in amniotic fluid.
与母兔和成年雄兔相比,胎儿主动脉中酰基辅酶A胆固醇酰基转移酶的活性明显较高。这种活性在1周龄时下降了50%。胎儿主动脉中的这种高活性:a)似乎不是由于血浆胆固醇水平的变化或主动脉中内源性抑制剂的后期发育,而是b)由于羊水中存在刺激因子。