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胎兔主动脉中高酰基辅酶A胆固醇酰基转移酶活性:羊水内存在刺激因子的证据。

High acyl-CoA cholesterol acyl transferase activity in fetal rabbit aorta: evidence for the presence of stimulating factor(s) in amniotic fluid.

作者信息

Rymaszewski Z, Sprinkle D J, Yunker R L, Subbiah M T

出版信息

Biochem Biophys Res Commun. 1985 Sep 16;131(2):707-11. doi: 10.1016/0006-291x(85)91295-1.

DOI:10.1016/0006-291x(85)91295-1
PMID:4052069
Abstract

The activity of Acyl CoA-cholesterol acyl transferase was markedly high in fetal aortas when compared to maternal and adult male rabbits. This activity dropped by 50% at 1 week of age. This high activity in fetal aorta a) did not appear to be due to changes in plasma cholesterol levels or to the later development of endogenous inhibitor in the aorta, but rather b) due to stimulatory factor(s) present in amniotic fluid.

摘要

与母兔和成年雄兔相比,胎儿主动脉中酰基辅酶A胆固醇酰基转移酶的活性明显较高。这种活性在1周龄时下降了50%。胎儿主动脉中的这种高活性:a)似乎不是由于血浆胆固醇水平的变化或主动脉中内源性抑制剂的后期发育,而是b)由于羊水中存在刺激因子。

相似文献

1
High acyl-CoA cholesterol acyl transferase activity in fetal rabbit aorta: evidence for the presence of stimulating factor(s) in amniotic fluid.胎兔主动脉中高酰基辅酶A胆固醇酰基转移酶活性:羊水内存在刺激因子的证据。
Biochem Biophys Res Commun. 1985 Sep 16;131(2):707-11. doi: 10.1016/0006-291x(85)91295-1.
2
Regulation of cholesterol metabolism in fetal rabbit aorta: role of amniotic fluid factors.胎兔主动脉胆固醇代谢的调节:羊水因子的作用。
Am J Physiol. 1988 Jul;255(1 Pt 2):H160-8. doi: 10.1152/ajpheart.1988.255.1.H160.
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Effect of a hypercholesterolaemic diet and a single injection of polyunsaturated phosphatidyl choline solution on the activities of lipolytic enzymes, acyl-CoA synthetase and acyl-CoA cholesterol acyl-transferase in rabbit tissues.高胆固醇饮食和单次注射多不饱和磷脂酰胆碱溶液对兔组织中脂解酶、酰基辅酶A合成酶和酰基辅酶A胆固醇酰基转移酶活性的影响。
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Effect of dietary fat saturation, cholesterol and cholestyramine on acyl-CoA: cholesterol acyltransferase activity in rabbit intestinal microsomes.膳食脂肪饱和度、胆固醇和消胆胺对兔肠微粒体中酰基辅酶A:胆固醇酰基转移酶活性的影响。
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Am J Clin Nutr. 1989 Jul;50(1):68-72. doi: 10.1093/ajcn/50.1.68.

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Morphological and smooth muscle cell phenotypic changes in fetal rabbit aorta during early development.胎儿兔主动脉早期发育过程中的形态学及平滑肌细胞表型变化
Basic Res Cardiol. 1989 May-Jun;84(3):259-67. doi: 10.1007/BF01907973.