Joy M, Haywood G A, Webb-Peploe M M
Br Heart J. 1985 Oct;54(4):448-51. doi: 10.1136/hrt.54.4.448.
A patient with severe variant angina that was refractory to conventional treatment became symptom free when she was treated with benzhexol (trihexyphenidyl hydrochloride), a cholinergic blocking agent used in the management of Parkinson's disease. There was a brief psychotic reaction when a large dose was taken and some memory impairment on the maintenance dose. Benzhexol should be used with caution but may prove to be an additional therapeutic agent in the management of severe variant angina.
一名患有严重变异型心绞痛且对传统治疗无效的患者，在接受用于帕金森病治疗的抗胆碱能药物苯海索（盐酸苯海索）治疗后症状消失。服用大剂量药物时出现了短暂的精神反应，维持剂量时出现了一些记忆障碍。使用苯海索时应谨慎，但可能被证明是治疗严重变异型心绞痛的一种辅助治疗药物。
