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全球变暖可能会增加阻塞性睡眠呼吸暂停的负担。

Global warming may increase the burden of obstructive sleep apnea.

作者信息

Lechat Bastien, Manners Jack, Pinilla Lucía, Reynolds Amy C, Scott Hannah, Vena Daniel, Bailly Sebastien, Fitton Josh, Toson Barbara, Kaambwa Billingsley, Adams Robert J, Pepin Jean-Louis, Escourrou Pierre, Catcheside Peter, Eckert Danny J

机构信息

Adelaide Institute for Sleep Health and FHMRI Sleep Health, College of Medicine and Public Health, Flinders University, Adelaide, Australia.

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

出版信息

Nat Commun. 2025 Jun 16;16(1):5100. doi: 10.1038/s41467-025-60218-1.

DOI:10.1038/s41467-025-60218-1
PMID:40523909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12170837/
Abstract

High ambient temperatures are associated with reduced sleep duration and quality, but effects on obstructive sleep apnea (OSA) severity are unknown. Here we quantify the effect of 24 h ambient temperature on nightly OSA severity in 116,620 users of a Food and Drug Administration-cleared nearable over 3.5 years. Wellbeing and productivity OSA burden for different levels of global warming were estimated. Globally, higher temperatures (99 vs. 25; 27.3 vs. 6.4 °C) were associated with a 45% higher probability of having OSA on a given night (mean [95% confidence interval]; 1.45 [1.44, 1.47]). Warming-related increase in OSA prevalence in 2023 was estimated to be associated with a loss of 788,198 (489,226, 1,087,170) healthy life years (in 29 countries), and a workplace productivity loss of 30 (21 to 40) billion United States dollars. Scenarios with projected temperatures ≥1.8 °C above pre-industrial levels would incur a further 1.2 to 3-fold increase in OSA burden by 2100.

摘要

高环境温度与睡眠时间和质量的降低有关,但对阻塞性睡眠呼吸暂停(OSA)严重程度的影响尚不清楚。在此,我们在3.5年多的时间里,对116,620名使用美国食品药品监督管理局批准的可穿戴设备的用户进行了量化,以研究24小时环境温度对夜间OSA严重程度的影响。我们还估计了不同全球变暖水平下的幸福感和生产力OSA负担。在全球范围内,较高温度(99华氏度 vs. 25华氏度;27.3摄氏度 vs. 6.4摄氏度)与特定夜晚患OSA的概率高出45%相关(均值[95%置信区间];1.45[1.44, 1.47])。据估计,2023年与变暖相关的OSA患病率增加与788,198(489,226, 1,087,170)个健康生命年的损失(在29个国家)以及30(21至40)亿美元的工作场所生产力损失相关。到2100年,预计温度比工业化前水平高出≥1.8摄氏度的情景将使OSA负担进一步增加1.2至3倍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcf4/12170837/ef73173a2b20/41467_2025_60218_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcf4/12170837/789667e0587d/41467_2025_60218_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcf4/12170837/d102317d8687/41467_2025_60218_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcf4/12170837/258947f969e0/41467_2025_60218_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcf4/12170837/c783eec7c476/41467_2025_60218_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcf4/12170837/ef73173a2b20/41467_2025_60218_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcf4/12170837/789667e0587d/41467_2025_60218_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcf4/12170837/d102317d8687/41467_2025_60218_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcf4/12170837/258947f969e0/41467_2025_60218_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcf4/12170837/c783eec7c476/41467_2025_60218_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcf4/12170837/ef73173a2b20/41467_2025_60218_Fig5_HTML.jpg

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