Clinical observation of pyogenic granuloma treated with combined long-pulse 1064nm Nd: YAG laser and pulsed CO2 laser photodynamic therapy.

To explore the clinical efficacy and safety of long-pulse 1064nm Nd: YAG laser combined with pulsed CO2 laser and topical application of aminolevulinic acid hydrochloride for photodynamic therapy in treating pyogenic granuloma. 20 patients with pyogenic granuloma were treated with a combination of long-pulse 1064nm Nd: YAG laser and pulsed CO2 laser along with photodynamic therapy using aminolevulinic acid hydrochloride. The efficacy, recurrence rate, and safety were observed at 1 month and 2 months post-treatment. All patients achieved a 100%cure rate and total effectiveness with a single treatment, with no infections, ulcers, or scars observed. Eight patients experienced mild pigmentation, which gradually resolved within one month, and there were no recurrences. The combined therapy of long-pulse 1064nm Nd: YAG laser and pulsed CO2 laser with photodynamic therapy is highly effective in treating pyogenic granuloma, with no recurrences and minimal adverse reactions, significantly improving patient satisfaction.