Cheng Jun, Yuan Hua, Fu Ronghua, Jin Pingliang, Huang Mengyu, Wu Zhiping, Bai Hanxiang, Huang Xiangqun, Zou Yun
Department of Plastic Surgery, Jiangxi Provincial Children's Hospital, Nanchang, China.
Sci Rep. 2025 Jan 22;15(1):2843. doi: 10.1038/s41598-025-85401-8.
Pyogenic granuloma (PG) is benign vascular lesions of the skin and mucous membranes that often involve the skin and mucous membranes, which often trouble patients due to its frequent bleeding. The traditional treatment is surgical removal, but its bleeding, pain, and trauma have led doctors to look for more minimally invasive methods. Between June 1, 2022 to March 1, 2024, we retrospectively analyzed 72 children with PG who were seen and treated in our department for long pulsed 1064 nm Nd: YAG laser (Gentle Nd: YAG laser) and sclerotherapy, respectively. The efficacy of the two treatments, pain scores, duration of surgery, and adverse events were assessed. The results showed no significant difference between the two groups in the efficacy of first treatment and the efficacy of secondary treatment. Although the procedure time was shorter in Gentle Nd: YAG laser group than in sclerotherapy group, the pain was more pronounced and the incidence of scarring was higher. No significant recurrence was detected in either group during the 6-month follow-up period. Gentle Nd: YAG laser and sclerotherapy for PG are sensitive, less invasive, and safe treatments. Sclerotherapy may be more acceptable to patients than Gentle Nd: YAG laser therapy because it is less painful and scarring is rare.
化脓性肉芽肿(PG)是皮肤和黏膜的良性血管病变,常累及皮肤和黏膜,因其频繁出血常给患者带来困扰。传统治疗方法是手术切除,但出血、疼痛和创伤促使医生寻求更微创的方法。在2022年6月1日至2024年3月1日期间,我们回顾性分析了72例在我科分别接受长脉冲1064nm Nd:YAG激光(Gentle Nd:YAG激光)和硬化治疗的PG患儿。评估了两种治疗方法的疗效、疼痛评分、手术持续时间和不良事件。结果显示,两组在首次治疗疗效和二次治疗疗效方面无显著差异。虽然Gentle Nd:YAG激光组的手术时间比硬化治疗组短,但其疼痛更明显,瘢痕形成发生率更高。在6个月的随访期内,两组均未检测到明显复发。Gentle Nd:YAG激光和硬化治疗对PG均敏感、侵入性小且安全。硬化治疗可能比Gentle Nd:YAG激光治疗更易被患者接受,因为其疼痛较轻且很少形成瘢痕。