Meyerhoff J L, Koller K J, Walczak D D, Coyle J T
Brain Res. 1985 Nov 4;346(2):392-6. doi: 10.1016/0006-8993(85)90877-7.
Rats were subjected to daily amygdaloid-kindling stimulation and sacrificed 48 h after their fifth stage-5 kindled seizure. Regional brain dissection was performed and the regions assayed for levels of N-acetyl-aspartyl-glutamate, an endogenous dipeptide specific to the brain and a putative excitatory neurotransmitter. Kindling produced significant increases in this dipeptide in the entorhinal cortex.
大鼠每日接受杏仁核点燃刺激，并在其第五次5级点燃性癫痫发作后48小时处死。进行脑区解剖，并检测各脑区中N-乙酰天门冬氨酰谷氨酸（一种脑内特有的内源性二肽及一种假定的兴奋性神经递质）的水平。点燃刺激使内嗅皮质中这种二肽水平显著升高。
