Andersen P, Christensen K M
Acta Med Scand. 1983;213(3):191-3. doi: 10.1111/j.0954-6820.1983.tb03715.x.
Antibodies to pigeon antigens were determined by double immunodiffusion and ELISA in 80 pigeon breeders without pigeon breeder's disease. Precipitating antibodies to pigeon serum and droppings were found in 5 and 8%, respectively, of 39 breeders who were smokers and in 46 and 51%, respectively, of 41 breeders who were nonsmokers (p less than 0.001). By ELISA, IgG antibodies to pigeon serum and droppings were detected in 44 and 54%, respectively, of smokers and in 81 and 85%, respectively, of nonsmokers (p less than 0.01). The antibody titres were generally higher in nonsmokers than in smokers. These findings may partly explain why allergic alveolitis occurs most often in nonsmokers.
采用双向免疫扩散法和酶联免疫吸附测定法，对80名未患养鸽者病的养鸽人进行了鸽抗原抗体检测。在39名吸烟的养鸽人中，分别有5%和8%的人对鸽血清和鸽粪产生沉淀抗体；而在41名不吸烟的养鸽人中，这一比例分别为46%和51%（p<0.001）。通过酶联免疫吸附测定法发现，吸烟养鸽人中分别有44%和54%的人对鸽血清和鸽粪检测出IgG抗体，不吸烟养鸽人中这一比例分别为81%和85%（p<0.01）。非吸烟者的抗体滴度总体上高于吸烟者。这些发现可能部分解释了为什么过敏性肺泡炎最常发生在不吸烟者中。
