Xu Guihua, Wu Guanrong, Du Zijing, Zhu Shanqing, Guo Yunxiang, Yu Honghua, Hu Yijun
Department of Ophthalmology, Huizhou Municipal Central Hospital, Huizhou, China.
Department of Ophthalmology, Guangdong Eye Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Front Med (Lausanne). 2021 Nov 18;8:732719. doi: 10.3389/fmed.2021.732719. eCollection 2021.
To investigate the distribution of white-to-white (WTW) corneal diameter and anterior chamber depth (ACD) in Chinese myopia patients. This was a cross-sectional observational study conducted at five ophthalmic centers. Anterior segment biometry was performed in 7,893 eyes of the 7,893 myopic patients using Pentacam, and the WTW and ACD were recorded. The distribution patterns of WTW and ACD were evaluated and the correlation between WTW and ACD was analyzed statistically. There were 4416 (55.95%) males and 3477 (44.05%) females. The age of the study population was 25.14 ± 5.41 years. Distribution of WTW was slightly positively skewed (Skewness = 0.0076, Kurtosis = 0.3944, KS = 0.020) with a mean of 11.65 ± 0.38 mm and a 95% normal range of 10.91-12.39 mm. A significant difference in WTW was found among different myopia groups ( < 0.001). The ACD was normally distributed (Skewness = 0.899, Kurtosis = 0.027, KS = 0.086). The mean ACD was 3.25 ± 0.26 mm and the 95% normal range of was 2.74-3.75 mm. A significant difference in ACD was also found among different myopia groups ( = 0.030). There was a significant correlation between WTW and ACD ( = 0.460, < 0.001). In our study, 95% of the Chinese myopic patients had a WTW within 10.91-12.39 mm and an ACD within 2.74-3.75 mm. ACD and WTW were significantly different among different myopia, gender and age groups. WTW was positively correlated with ACD.
探讨中国近视患者白对白(WTW)角膜直径和前房深度(ACD)的分布情况。这是一项在五个眼科中心进行的横断面观察性研究。使用Pentacam对7893例近视患者的7893只眼进行眼前节生物测量,并记录WTW和ACD。评估WTW和ACD的分布模式,并对WTW和ACD之间的相关性进行统计学分析。男性4416例(55.95%),女性3477例(44.05%)。研究人群的年龄为25.14±5.41岁。WTW的分布呈轻度正偏态(偏度=0.0076,峰度=0.3944,KS=0.020),平均值为11.65±0.38mm,95%正常范围为10.91-12.39mm。不同近视组间WTW存在显著差异(<0.001)。ACD呈正态分布(偏度=0.899,峰度=0.027,KS=0.086)。平均ACD为3.25±0.26mm,95%正常范围为2.74-3.75mm。不同近视组间ACD也存在显著差异(=0.030)。WTW和ACD之间存在显著相关性(=0.460,<0.001)。在我们的研究中,95%的中国近视患者WTW在10.91-12.39mm之间,ACD在2.74-3.75mm之间。ACD和WTW在不同近视、性别和年龄组之间存在显著差异。WTW与ACD呈正相关。