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利用转化科学效益模型来加强对临床与转化科学奖(CTSA)中心支持的研究的影响规划和评估。

Leveraging the translational science benefits model to enhance planning and evaluation of impact in CTSA hub-supported research.

作者信息

Molzhon Andrea, Dillon Pamela M, DiazGranados Deborah

机构信息

C. Kenneth and Dianne Wright Center for Clinical and Translational Research, Office of the Vice President for Research and Innovation, Virginia Commonwealth University, Richmond, VA, United States.

Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, United States.

出版信息

Front Public Health. 2025 Jun 5;13:1593920. doi: 10.3389/fpubh.2025.1593920. eCollection 2025.

Abstract

INTRODUCTION

Increasingly, the public, policymakers, and funders expect clinical research to show tangible effects on public health. However, assessing research impact is challenging. Most researchers are not trained to consider the broad-ranging impacts of their work. The TSBM is a conceptual framework that includes four domains of impact: clinical, community, economic, and policy. We assess the utility and acceptability of using a survey based on the TSBM as a means to help researchers identify their potential research impacts.

METHODS

CTSA program-supported investigators self-reported the potential benefits of their research projects in an electronic survey based on the TSBM. Responses were reviewed and scored by program evaluators. Survey acceptability was measured by response and completion rates; utility was measured by comparing benefits identified in the survey but not described in the researcher's grant application; and quality was measured by the degree of congruence between investigators' responses and evaluators' determinations regarding the potential benefits of the research.

RESULTS

Of the investigators invited to participate, 67% completed the survey. Half of the investigators identified at least one benefit from their research not described in their research proposals. The rate of agreement across all responses between the investigators and the evaluators was 60%.

DISCUSSION

Our study showed that a survey based on the framework of the TSBM was an acceptable and useful tool to help investigators identify research impact. However, our work also suggested that there are opportunities to educate investigators especially about the long-term, broad-reaching effects of their work. Ultimately, this work may help researchers conceptualize and realize the public health impact of their research.

摘要

引言

公众、政策制定者和资助者越来越期望临床研究能对公众健康产生切实影响。然而,评估研究影响具有挑战性。大多数研究人员未接受过考虑其工作广泛影响的培训。TSBM是一个概念框架,包括四个影响领域:临床、社区、经济和政策。我们评估使用基于TSBM的调查作为帮助研究人员识别其潜在研究影响的手段的效用和可接受性。

方法

CTSA项目支持的研究人员在基于TSBM的电子调查中自我报告其研究项目的潜在益处。项目评估人员对回复进行审查和评分。通过回复率和完成率衡量调查的可接受性;通过比较调查中识别出但研究人员的资助申请中未描述的益处来衡量效用;通过研究人员的回复与评估人员关于研究潜在益处的判定之间的一致程度来衡量质量。

结果

受邀参与的研究人员中,67%完成了调查。一半的研究人员从其研究中识别出至少一项其研究提案中未描述的益处。研究人员和评估人员所有回复之间的一致率为60%。

讨论

我们的研究表明,基于TSBM框架的调查是帮助研究人员识别研究影响的可接受且有用的工具。然而,我们的工作也表明有机会对研究人员进行教育,尤其是关于其工作的长期、广泛影响。最终,这项工作可能有助于研究人员将其研究的公共卫生影响概念化并实现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/795a/12176810/aca2d2851c97/fpubh-13-1593920-g001.jpg

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