Phan Hiep S, Strate Lisa L
Division of Gastroenterology and Hepatology, School of Medicine and Public Health, University of Wisconsin, 1685 Highland Avenue, Madison, WI, 53705, USA.
Curr Gastroenterol Rep. 2025 Jun 21;27(1):42. doi: 10.1007/s11894-025-00986-4.
While societal guidelines help direct management of diverticulitis and diverticular bleeding broadly, our review focuses on the latest data for nuanced care of older patients affected by these conditions.
Diverticulitis in older patients can present with non-specific symptoms so a broad work up is recommended. Once diagnosed, those with uncomplicated disease (Hinchey Class 0 or 1a) can be safely managed without antibiotics or admission depending on frailty and comorbidities. Most older patients with complicated diverticulitis (abscess, perforation or obstruction) should be hospitalized. Elective or emergent surgery for complicated disease (Hinchey Class 1b-4) is associated with higher morbidity and mortality, particularly in older patients. The risk of diverticular bleeding and re-bleeding significantly increases with age, potentially due to the use of nonsteroidal anti-inflammatory drugs (NSAIDs) and anticoagulants. Diverticular disease and its associated complications disproportionately affect older adults. Management should focus on resuscitation, having low threshold for comprehensive work up and re-evaluating medication use for comorbid conditions to prevent recurrence.
虽然社会指南有助于广泛指导憩室炎和憩室出血的管理,但我们的综述重点关注受这些疾病影响的老年患者细致护理的最新数据。
老年患者的憩室炎可能表现为非特异性症状,因此建议进行全面检查。一旦确诊,根据虚弱程度和合并症,无并发症的患者(辛奇分类0或1a)无需使用抗生素或住院即可安全管理。大多数患有复杂憩室炎(脓肿、穿孔或梗阻)的老年患者应住院治疗。复杂疾病(辛奇分类1b - 4)的择期或急诊手术与较高的发病率和死亡率相关,尤其是在老年患者中。憩室出血和再出血的风险随着年龄的增长显著增加,这可能与使用非甾体抗炎药(NSAIDs)和抗凝剂有关。憩室病及其相关并发症对老年人的影响尤为严重。管理应侧重于复苏,对全面检查保持低门槛,并重新评估合并症的用药情况以预防复发。