Balasch J, Vanrell J A, Creus M, Márquez M, González-Merlo J
Fertil Steril. 1985 Nov;44(5):699-701. doi: 10.1016/s0015-0282(16)48990-9.
We studied endometrial luteal phase in specimens from 660 biopsies done in 300 patients from our infertility clinic. A minimum of two (240 women) or three (60 women) endometrial biopsy specimens from separate cycles were taken regardless of the previous histologic findings in all patients. Statistical analysis of results by the McNemar and the Cochran Q tests for the significance of changes leads us to conclude that a minimum of two, and even three, endometrial biopsy specimens are needed for diagnosis of luteal phase deficiency.
我们对来自不孕症门诊300例患者的660份活检标本的子宫内膜黄体期进行了研究。无论所有患者之前的组织学检查结果如何，均从不同周期采集至少两份（240名女性）或三份（60名女性）子宫内膜活检标本。通过McNemar检验和Cochran Q检验对结果进行统计学分析以确定变化的显著性，结果使我们得出结论，诊断黄体期缺陷至少需要两份甚至三份子宫内膜活检标本。
