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重症监护病房幸存者的长期生活质量

Long-Term Quality of Life Among Intensive Care Units Survivors.

作者信息

Aljohani Hassan Y, Albarak Naif A, Alanazi Talal A, Alabdulsalam Muhnad A, Alzahrani Rayan A, Algarni Saleh S, Alotaibi Tareq F, Alqahtani Mohammed M, Alqahtani Mobarak K, Ismaeil Taha T, Olayan Lafi H

机构信息

Department of Respiratory Therapy, King Saud bin Abdulaziz University for Health Sciences (KSAU-HS), Riyadh, Saudi Arabia.

King Abdullah International Medical Research Centre (KAIMRC), Riyadh, Saudi Arabia.

出版信息

Risk Manag Healthc Policy. 2025 Jun 17;18:1969-1978. doi: 10.2147/RMHP.S517832. eCollection 2025.

Abstract

BACKGROUND

The long-term health-related quality of life (HRQoL) of intensive care unit (ICU) survivors is a key concern. This study investigates HRQoL among ICU survivors in Saudi Arabia, highlighting its importance for advancing healthcare and improving outcomes.

METHODS

A cross-sectional study was conducted among ICU survivors and a control healthy group. Participants were aged ≥18 years, with ICU survivors discharged for at least six months excluding individuals with severe cognitive impairments or mental illness. The SF-36 questionnaire assessed HRQoL across eight domains, with data collected from a tertiary hospital in Riyadh. Statistical analysis included the Mann-Whitney -test, the Fisher exact, and multiple linear regression.

RESULTS

Data from 151 ICU survivors and 181 controls were analyzed. Chronic diseases were more common among ICU survivors (51.7% vs 23.8%, p=0.00). Independent of chronic diseases, ICU survivors had significantly lower scores in HRQoL. Prolonged ICU stays were associated with worse quality outcomes. Additionally, being discharged for ≥ seven months improved general health (p=0.05). ICU survivors displayed notably lower scores in physical functioning (65 [IQR 55] vs 80 [IQR 45], p=0.00), limitations due to physical health (25 [IQR 100] vs 100 [IQR 75], p=0.00), limitations due to emotional problems (33.33 [IQR 100] vs 66.67 [IQR 100], p=0.00), less social functioning (62.5 [IQR 50] vs 75 [IQR 38], p=7.00), more pain 67.5 [IQR 45] vs 80 [IQR 33] (p=0.00), and general health (55 [IQR 25] vs 65 [IQR 23], p=0.00).

CONCLUSION

ICU survivors experience significant HRQoL impairments exacerbated by prolonged ICU stays, highlighting the need for early and comprehensive rehabilitation services. The low utilization of these rehabilitation services suggests a need to provide access and quality for tailored early rehabilitation services to improve ICU survivors' long-term HRQoL.

摘要

背景

重症监护病房(ICU)幸存者与健康相关的长期生活质量(HRQoL)是一个关键问题。本研究调查了沙特阿拉伯ICU幸存者的HRQoL,强调了其对推进医疗保健和改善治疗结果的重要性。

方法

对ICU幸存者和健康对照组进行了一项横断面研究。参与者年龄≥18岁,ICU幸存者出院至少六个月,排除有严重认知障碍或精神疾病的个体。SF-36问卷评估了八个领域的HRQoL,数据来自利雅得的一家三级医院。统计分析包括Mann-Whitney检验、Fisher精确检验和多元线性回归。

结果

分析了151名ICU幸存者和181名对照的数据。慢性病在ICU幸存者中更为常见(51.7%对23.8%,p=0.00)。独立于慢性病,ICU幸存者的HRQoL得分显著较低。ICU住院时间延长与较差的质量结果相关。此外,出院≥七个月可改善总体健康状况(p=0.05)。ICU幸存者在身体功能(65[四分位间距55]对80[四分位间距45],p=0.00)、因身体健康导致的限制(25[四分位间距100]对100[四分位间距75],p=0.00)、因情绪问题导致的限制(33.33[四分位间距100]对66.67[四分位间距100],p=0.00)、社交功能较少(62.5[四分位间距50]对75[四分位间距38],p=7.00)、疼痛更多(67.5[四分位间距45]对80[四分位间距33],p=0.00)和总体健康(55[四分位间距25]对65[四分位间距23],p=0.00)方面的得分明显较低。

结论

ICU幸存者经历了显著的HRQoL损害,ICU住院时间延长会加剧这种损害,突出了早期和全面康复服务的必要性。这些康复服务的低利用率表明需要提供可及的、高质量的定制早期康复服务,以改善ICU幸存者的长期HRQoL。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9da5/12182076/2cb32e62ee22/RMHP-18-1969-g0001.jpg

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