D'Ermo F, Secchi A G
Klin Monbl Augenheilkd. 1977 Mar;170(3):433-6.
Phospholipase A and Lysophosphatidylcholine (LPC) have been shown harmful for normal lens permeability, inducing an efflux of intracellular macromolecules in organ cultures. These findings, superimposible to what has been shown in the lens for complement-dependent immune damage, along with the hypothesis that the cytotoxicity of complement is mediated by a phospholipase, are considered relevant as far as the pathogenesis of complicated cataracts in "immune" uveitis and the selfmaintenance of recurrent autoimmune (to lens proteins) anterior uveitis are concerned.
磷脂酶A和溶血磷脂酰胆碱（LPC）已被证明对正常晶状体通透性有害，可在器官培养中诱导细胞内大分子外流。这些发现与晶状体中补体依赖性免疫损伤的表现相似，再加上补体细胞毒性由磷脂酶介导的假说，就“免疫性”葡萄膜炎中复杂性白内障的发病机制以及复发性自身免疫性（针对晶状体蛋白）前葡萄膜炎的自我维持而言，这些发现被认为具有重要意义。
